Mengrong Xie, Ruiqin Ni, Jingying Zhang, Mingmei Zhong, Ping Wang
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Eosinophilic Granulomatous Polyangiitis with Autoimmune Hemolytic Anemia: A Case Report and Review of the Literature.
EGPA can affect multiple organ systems, typically presenting with respiratory symptoms as the initial manifestation. The absence of specific diagnostic biomarkers makes it prone to misdiagnosis. This article describes a 40-year-old female patient who presented with asthma-like symptoms, neurosensory impairment, anemia, peripheral blood eosinophilia, and pulmonary involvement. The patient was diagnosed with EGPA combined with AIHA. After ineffective treatment with glucocorticoids alone, the patients' symptoms were relieved by the addition of the immunosuppressant cyclophosphamide. Cyclophosphamide was discontinued after the total dose reached 7g and the patient relapsed. Subsequent treatment for the patients involved a combination of glucocorticoids and MMF, with no evidence of recurrence. This case is relatively rare in clinical practice, and fortunately the final treatment effect is satisfactory.
期刊介绍:
An international, peer-reviewed journal publishing original research, reports, editorials and commentaries on the following topics: Asthma; Pulmonary physiology; Asthma related clinical health; Clinical immunology and the immunological basis of disease; Pharmacological interventions and new therapies.
Although the main focus of the journal will be to publish research and clinical results in humans, preclinical, animal and in vitro studies will be published where they shed light on disease processes and potential new therapies.