【撤回】丹皮酚通过下调ERBB2和抑制NF - κB信号通路诱导胃癌细胞系SGC - 7901细胞凋亡。

IF 5.7 3区 医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL
International journal of molecular medicine Pub Date : 2025-06-01 Epub Date: 2025-04-17 DOI:10.3892/ijmm.2025.5532
Jun Fu, Luhua Yu, Jie Luo, Rui Huo, Bing Zhu
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引用次数: 0

摘要

在上述论文发表后,一位关心的读者提请编辑注意,关于图7(第1479页)所示的流式细胞术图,尽管数据点的数量随着paenol浓度的增加而增加,但在面板上的点的图案是相似的,如果这些实验是分开进行的,就不会预料到结果。这表明这些实验的执行方式存在根本缺陷。《国际分子医学杂志》的编辑已经决定,由于对所呈现的数据缺乏信心,这篇论文应该从该杂志上撤回。作者被要求对这些担忧作出解释,但编辑部没有收到答复。对于由此给读者带来的不便,本刊编辑深表歉意。[国际分子医学杂志42:1473‑1483,2018;DOI: 10.3892 / ijmm.2018.3704]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Retracted] Paeonol induces the apoptosis of the SGC‑7901 gastric cancer cell line by downregulating ERBB2 and inhibiting the NF‑κB signaling pathway.

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the flow cytometric plots shown in Fig. 7 on p. 1479, although the number of data points increased with an increasing concentration of paenol, the patterning of the dots were similar comparing across the panels, which would not have been anticipated as the result if these experiments had been performed discretely, suggesting a fundamental flaw in the way in which these experiments were performed. The Editor of International Journal of Molecular Medicine has decided that this paper should be retracted from the Journal on account of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Molecular Medicine 42: 1473‑1483, 2018; DOI: 10.3892/ijmm.2018.3704].

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来源期刊
International journal of molecular medicine
International journal of molecular medicine 医学-医学:研究与实验
CiteScore
12.30
自引率
0.00%
发文量
124
审稿时长
3 months
期刊介绍: The main aim of Spandidos Publications is to facilitate scientific communication in a clear, concise and objective manner, while striving to provide prompt publication of original works of high quality. The journals largely concentrate on molecular and experimental medicine, oncology, clinical and experimental cancer treatment and biomedical research. All journals published by Spandidos Publications Ltd. maintain the highest standards of quality, and the members of their Editorial Boards are world-renowned scientists.
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