Konstantinos Prokopidis, Amy Nortcliffe, Chukwuma Okoye, Massimo Venturelli, Gregory Y. H. Lip, Masoud Isanejad
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引用次数: 0
摘要
目的：本研究的目的是比较心力衰竭合并虚弱患者与非虚弱患者因心力衰竭（HHF）住院时间（LoS）和先前住院时间的差异。方法与结果：从成立到2024年8月，检索PubMed、Scopus、Web of Science和Cochrane Library。为了研究HF患者的LoS和HHF的相关性，采用随机效应模型（CRD42024570604）进行了荟萃分析。我们的主要分析表明，与没有虚弱的患者相比，虚弱患者的LoS显著增加[n = 10；平均差（MD）： 3.67；95% CI: 2.26-5.08, I2 = 93%, P = 81%， P结论：虚弱患者的LoS更长，HHF更频繁，强调需要早期，有针对性的干预措施来管理虚弱，这可能主要归因于衰老和合并症相关状态。
Length of stay and prior heart failure admission in frailty and heart failure: A systematic review and meta-analysis
Aims
The aim of this study was to compare the differences in length of stay (LoS) and prior hospitalization due to heart failure (HHF) in patients with HF and frailty versus without frailty.
Methods and results
From inception until August 2024, PubMed, Scopus, Web of Science and Cochrane Library were searched. To examine the association related to LoS and HHF in patients with HF, a meta-analysis using a random-effects model was conducted (CRD42024570604). Our main analysis demonstrated a significantly increased LoS in patients with frailty versus those without frailty [n = 10; mean difference (MD): 3.67; 95% CI: 2.26–5.08, I2 = 93%, P < 0.01]. Likewise, patients with frailty had significantly increased odds of HHF [n = 17; odds ratio (OR): 1.76; 95% CI: 1.50–2.07, I2 = 81%, P < 0.01]. Risk of bias assessment of the included studies was overall fair, while Egger's test showed publication bias regarding studies that examined LoS (P = 0.02).
Conclusions
Patients with frailty have longer LoS and more frequent HHF, underscoring the need for early, targeted interventions to manage frailty that may be attributed primarily to ageing and comorbidity-related status.
期刊介绍：
ESC Heart Failure is the open access journal of the Heart Failure Association of the European Society of Cardiology dedicated to the advancement of knowledge in the field of heart failure. The journal aims to improve the understanding, prevention, investigation and treatment of heart failure. Molecular and cellular biology, pathology, physiology, electrophysiology, pharmacology, as well as the clinical, social and population sciences all form part of the discipline that is heart failure. Accordingly, submission of manuscripts on basic, translational, clinical and population sciences is invited. Original contributions on nursing, care of the elderly, primary care, health economics and other specialist fields related to heart failure are also welcome, as are case reports that highlight interesting aspects of heart failure care and treatment.
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