自我给药与淋巴水肿治疗师给药的复杂减充血治疗方案在乳腺癌相关淋巴水肿:一项3个月随访的非自卑随机对照试验。

IF 3 3区 医学 Q2 ONCOLOGY
Breast Cancer Research and Treatment Pub Date : 2025-07-01 Epub Date: 2025-05-06 DOI:10.1007/s10549-025-07709-3
Sukriye Cansu Gultekin, Didem Karadibak, Ahmet Burak Cakir, Zeynep Gulsum Guc, Tugba Yavuzsen
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引用次数: 0

摘要

目的:本研究的目的是证明,在治疗乳腺癌相关淋巴水肿(BCRL)患者的淋巴水肿和健康相关结局方面,自我给予的复杂减充血治疗(CDT)方案并不逊于经认证的淋巴水肿治疗师(CLT)给予的CDT。方法:50例BCRL患者随机分为两个实验组:(1)clt给药CDT组(n = 25)和自我给药CDT组(n = 25)。CDT在两种实验条件下采用多模式方法,包括患者教育、手工淋巴引流、多层包扎、治疗练习和皮肤/指甲护理。采用围度测量评估淋巴水肿严重程度,采用数值评定量表评估bcrl相关症状。以下测量方法用于评估与健康相关的结果:通用关节活动度测量仪(ROMs)、手掌握力测量仪(手掌外周肌肉力量)、手臂、肩膀和手部残疾(DASH)残疾水平问卷、国际体育活动问卷-短表(IPAQ-SF)体育活动水平、个人力量检查表(CIS)疲劳和上肢淋巴水肿生活质量问卷(ULL-27)生活质量。结果:CDT治疗后,两组患者淋巴水肿严重程度及淋巴水肿相关症状均明显减轻(p < 0.05)。随访3个月,自我给予CDT组淋巴水肿、僵硬、沉重和疲劳的严重程度均有所降低(p < 0.05)。结论:目前的研究结果表明,在淋巴水肿的管理和减少淋巴水肿相关残疾方面,自我给药CDT方案并不亚于clt给药CDT。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Self-administered versus lymphedema therapist-administered complex decongestive therapy protocol in breast cancer-related lymphedema: a non-inferiority randomized controlled trial with three-month follow-up.

Purpose: The aim of this study was to demonstrate that a self-administered complex decongestive therapy (CDT) protocol is not inferior to certified lymphedema therapist (CLT)-administered CDT in the management of lymphedema and health-related outcomes in patients with breast cancer-related lymphedema (BCRL).

Methods: Fifty patients with BCRL were randomly assigned to two experimental groups: (1) a CLT-administered CDT group (n = 25) or a self-administered CDT group (n = 25). CDT was a multimodal approach in two experimental conditions consisting of patient education, manual lymph drainage, multi-layer bandaging, therapeutic exercises and skin/nail care. Lymphedema severity was assessed using circumference measurement, and BCRL-related symptoms were assessed using a numerical rating scale. The following measurement methods were used to assess health-related outcomes: universal goniometer for range of motion (ROMs), hand grip dynamometer for peripheral muscle strength, disabilities of the arm, shoulder and hand (DASH) questionnaire for disability level, International Physical Activity Questionnaire-Short Form (IPAQ-SF) for physical activity level, the checklist for individual strength (CIS) for fatigue and upper limb lymphedema quality of life questionnaire (ULL-27) for quality of life.

Results: Following CDT, there was a significant decrease in lymphedema severity and lymphedema-related symptoms in both groups (p < 0.001). There was no significant difference between the groups regarding the mean difference in health-related outcomes following CDT (post-treatment-baseline) (p < 0.05). Lymphedema severity and symptoms remained stable during the 3-month follow-up periods in the CLT-administered CDT group (p > 0.05). There was a decrease in the severity of lymphedema, stiffness, heaviness and fatigue in the self-administered CDT group at 3-month follow-up (p < 0.05), while pain and tingling remained unchanged (p > 0.05).

Conclusion: The present findings demonstrated self-administered CDT protocol is not inferior to CLT-administered CDT in the management of lymphedema and reduction of lymphedema-related disabilities.

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来源期刊
CiteScore
6.80
自引率
2.60%
发文量
342
审稿时长
1 months
期刊介绍: Breast Cancer Research and Treatment provides the surgeon, radiotherapist, medical oncologist, endocrinologist, epidemiologist, immunologist or cell biologist investigating problems in breast cancer a single forum for communication. The journal creates a "market place" for breast cancer topics which cuts across all the usual lines of disciplines, providing a site for presenting pertinent investigations, and for discussing critical questions relevant to the entire field. It seeks to develop a new focus and new perspectives for all those concerned with breast cancer.
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