Chenshan Huang, Yuanjiao Yan, Wilson Wai San Tam, Wenqian Sun, Yu Ye, Nafang Wang, Yanhong Shi, Ziping Zhu, Danting Chen, Lin Chen, Junyu Zhao, Rong Lin, Hong Li
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Four nursing homes in two districts of a city in southeastern China were randomly assigned (1:1) to either the intervention or the control group. The intervention group received a 14-week, 28-session integrated social-art program structured around theme-based group activities, while the control group received usual care, including assistance with daily living activities, basic medical care, recreational activities, and environmental cleaning. Quantitative outcomes were measured at baseline (T0), immediately post-intervention (T1), and at 24-week follow-up (T2), with global cognitive function as the primary outcome, and specific cognitive functions, psychosocial indicators, functional abilities, and quality of life as secondary outcomes. Qualitative interviews were conducted post-intervention to explore the reasons underlying the observed variations in efficacy.</p><p><strong>Results: </strong>Eighty older adults with MCI (median age 86.50 years) participated, with an average attendance rate of 86.25% in the intervention group. Intention-to-treat analyses revealed a significant improvement in global cognitive function at T1 in the intervention group compared to the control group (β = 2.85; 95%CI [1.27, 4.44], P < 0.001); however, this effect was not sustained at T2. No significant improvements were observed in psychosocial indicators, functional abilities, or quality of life (P > 0.05). Qualitative findings indicated that structured, sequential tasks and professional guidance contributed to short-term cognitive gains, whereas age-related health issues and limited ongoing engagement impeded the durability of these benefits.</p><p><strong>Conclusions: </strong>The 14-week integrated social-art intervention appears feasible and may promote short-term cognitive activation in institutionalized older adults with MCI, though its benefits were not sustained at follow-up. 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引用次数: 0
摘要
背景:轻度认知障碍(MCI)在养老院老年人中的患病率上升,需要有效的干预措施来减缓痴呆的进展。综合社会艺术干预在增强认知功能和减少社会孤立方面显示出希望。本研究旨在评估这种干预对老年轻度认知障碍患者认知和心理社会结局的影响。方法:采用解释性顺序混合方法研究,包括整群随机对照试验(RCT)和描述性定性研究。在中国东南部某城市的两个区,四家养老院被随机(1:1)分配到干预组或对照组。干预组接受为期14周、28期的综合社会艺术项目,以主题为基础的小组活动为中心,而对照组接受常规护理,包括日常生活活动、基本医疗护理、娱乐活动和环境清洁。定量结果在基线(T0)、干预后立即(T1)和24周随访(T2)时进行测量,以总体认知功能为主要结果,特定认知功能、社会心理指标、功能能力和生活质量为次要结果。在干预后进行了定性访谈,以探讨观察到的疗效变化的原因。结果:干预组老年轻度认知损伤患者80例(中位年龄86.50岁),平均出勤率86.25%。意向治疗分析显示,与对照组相比,干预组在T1时整体认知功能有显著改善(β = 2.85;95%ci [1.27, 4.44], p 0.05)。定性研究结果表明,结构化、连续的任务和专业指导有助于短期的认知收益,而与年龄相关的健康问题和有限的持续参与阻碍了这些收益的持久性。结论:为期14周的综合社会艺术干预似乎是可行的,并且可能促进患有轻度认知障碍的制度化老年人的短期认知激活,尽管其益处在随访中并未持续。未来的研究应探讨维持认知改善的策略,并探索改进措施,以提高这一弱势群体的更广泛的临床结果。试验注册:该试验已于2022年6月30日在中国临床试验注册中心前瞻性注册,注册号为ChiCTR2200061681。
Effects of an integrated social-art intervention on cognitive and psychosocial outcomes among older adults with mild cognitive impairment in nursing homes: a mixed methods study.
Background: The rising prevalence of mild cognitive impairment (MCI) among older adults in nursing homes necessitates effective interventions to slow the progression to dementia. Integrated social-art interventions have shown promise in enhancing cognitive function and reducing social isolation. This study aimed to evaluate the effects of such an intervention on cognitive and psychosocial outcomes in older adults with MCI.
Methods: An explanatory sequential mixed-methods study was conducted, comprising a cluster randomized controlled trial (RCT) and a descriptive qualitative study. Four nursing homes in two districts of a city in southeastern China were randomly assigned (1:1) to either the intervention or the control group. The intervention group received a 14-week, 28-session integrated social-art program structured around theme-based group activities, while the control group received usual care, including assistance with daily living activities, basic medical care, recreational activities, and environmental cleaning. Quantitative outcomes were measured at baseline (T0), immediately post-intervention (T1), and at 24-week follow-up (T2), with global cognitive function as the primary outcome, and specific cognitive functions, psychosocial indicators, functional abilities, and quality of life as secondary outcomes. Qualitative interviews were conducted post-intervention to explore the reasons underlying the observed variations in efficacy.
Results: Eighty older adults with MCI (median age 86.50 years) participated, with an average attendance rate of 86.25% in the intervention group. Intention-to-treat analyses revealed a significant improvement in global cognitive function at T1 in the intervention group compared to the control group (β = 2.85; 95%CI [1.27, 4.44], P < 0.001); however, this effect was not sustained at T2. No significant improvements were observed in psychosocial indicators, functional abilities, or quality of life (P > 0.05). Qualitative findings indicated that structured, sequential tasks and professional guidance contributed to short-term cognitive gains, whereas age-related health issues and limited ongoing engagement impeded the durability of these benefits.
Conclusions: The 14-week integrated social-art intervention appears feasible and may promote short-term cognitive activation in institutionalized older adults with MCI, though its benefits were not sustained at follow-up. Future research should investigate strategies for maintaining cognitive improvements and explore modifications to enhance broader clinical outcomes in this vulnerable population.
Trial registration: The trial was prospectively registered at the Chinese Clinical Trials Registry with the registration number ChiCTR2200061681 on 30 June 2022.
期刊介绍:
BMC Medicine is an open access, transparent peer-reviewed general medical journal. It is the flagship journal of the BMC series and publishes outstanding and influential research in various areas including clinical practice, translational medicine, medical and health advances, public health, global health, policy, and general topics of interest to the biomedical and sociomedical professional communities. In addition to research articles, the journal also publishes stimulating debates, reviews, unique forum articles, and concise tutorials. All articles published in BMC Medicine are included in various databases such as Biological Abstracts, BIOSIS, CAS, Citebase, Current contents, DOAJ, Embase, MEDLINE, PubMed, Science Citation Index Expanded, OAIster, SCImago, Scopus, SOCOLAR, and Zetoc.