{"title":"外伤性颈脊髓损伤后气管切开术时机与预后的关系。","authors":"Syed Shaheer Ali, Troy Coaston, Konmal Ali, Saad Mallick, Esteban Aguayo, Areti Tillou, Peyman Benharash, Galinos Barmparas","doi":"10.1177/00031348251337147","DOIUrl":null,"url":null,"abstract":"<p><p>BackgroundPatients with cervical spinal cord injury (CSCI) often require tracheostomy due to a prolonged ventilator dependence. However, optimal time for tracheostomy remains controversial.MethodsAll adult patients (≥18 years) with CSCI who underwent tracheostomy were identified in the 2018-2021 Trauma Quality Improvement Program database. The median time to tracheostomy of the entire sample was found in which patients were categorized into <i>Early</i> (≤10 days) and <i>Delayed</i> (>10 days) cohorts based on whether they were below or above the median. Multivariable regression models were developed to examine the association between tracheostomy timing and clinical outcomes including pneumonia, unplanned intubation, decubitus ulcer, deep vein thrombosis, and in-hospital mortality.ResultsOf 3545 patients, 43.0% underwent tracheostomy within 10 days of admission. Compared to <i>Delayed, Early</i> was more commonly younger (51 [32-65] vs 58 years [40-77]; <i>P</i> < 0.001) and privately insured (38.6 vs 37.8%, <i>P</i> < 0.001). Upon adjustment, severe facial injury and a greater injury severity score (ISS) were associated with increased odds of early tracheostomy. Additionally, early tracheostomy was linked with reduced odds of pneumonia (Adjusted Odds Ratio [AOR] 0.70, 95% 0.62-0.82), decubitus ulcer (AOR 0.61, 95% CI 0.53-0.71), and unplanned intubation (AOR 0.43, 95% CI 0.37-0.49). Tracheostomy timing did not alter risk of in-hospital mortality (<i>Early</i>: AOR 1.08, 95% CI 0.86-1.35).DiscussionEarly tracheostomy in CSCI patients was associated with lower risk of complications, without differences in adjusted mortality rate. These findings suggest that early tracheostomy may improve acute outcomes in CSCI patients. Further prospective research is warranted to inform standardized care pathways.</p>","PeriodicalId":7782,"journal":{"name":"American Surgeon","volume":" ","pages":"1613-1619"},"PeriodicalIF":0.9000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association of Tracheostomy Timing With Outcomes Following Traumatic Cervical Spinal Cord Injury.\",\"authors\":\"Syed Shaheer Ali, Troy Coaston, Konmal Ali, Saad Mallick, Esteban Aguayo, Areti Tillou, Peyman Benharash, Galinos Barmparas\",\"doi\":\"10.1177/00031348251337147\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>BackgroundPatients with cervical spinal cord injury (CSCI) often require tracheostomy due to a prolonged ventilator dependence. However, optimal time for tracheostomy remains controversial.MethodsAll adult patients (≥18 years) with CSCI who underwent tracheostomy were identified in the 2018-2021 Trauma Quality Improvement Program database. The median time to tracheostomy of the entire sample was found in which patients were categorized into <i>Early</i> (≤10 days) and <i>Delayed</i> (>10 days) cohorts based on whether they were below or above the median. Multivariable regression models were developed to examine the association between tracheostomy timing and clinical outcomes including pneumonia, unplanned intubation, decubitus ulcer, deep vein thrombosis, and in-hospital mortality.ResultsOf 3545 patients, 43.0% underwent tracheostomy within 10 days of admission. Compared to <i>Delayed, Early</i> was more commonly younger (51 [32-65] vs 58 years [40-77]; <i>P</i> < 0.001) and privately insured (38.6 vs 37.8%, <i>P</i> < 0.001). Upon adjustment, severe facial injury and a greater injury severity score (ISS) were associated with increased odds of early tracheostomy. Additionally, early tracheostomy was linked with reduced odds of pneumonia (Adjusted Odds Ratio [AOR] 0.70, 95% 0.62-0.82), decubitus ulcer (AOR 0.61, 95% CI 0.53-0.71), and unplanned intubation (AOR 0.43, 95% CI 0.37-0.49). Tracheostomy timing did not alter risk of in-hospital mortality (<i>Early</i>: AOR 1.08, 95% CI 0.86-1.35).DiscussionEarly tracheostomy in CSCI patients was associated with lower risk of complications, without differences in adjusted mortality rate. These findings suggest that early tracheostomy may improve acute outcomes in CSCI patients. Further prospective research is warranted to inform standardized care pathways.</p>\",\"PeriodicalId\":7782,\"journal\":{\"name\":\"American Surgeon\",\"volume\":\" \",\"pages\":\"1613-1619\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American Surgeon\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/00031348251337147\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/4/24 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Surgeon","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00031348251337147","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/24 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
摘要
背景:由于长期依赖呼吸机,颈脊髓损伤(CSCI)患者往往需要气管切开术。然而,气管切开术的最佳时间仍有争议。方法所有接受气管切开术的CSCI成年患者(≥18岁)均纳入2018-2021年创伤质量改善计划数据库。根据患者是否低于或高于中位数,将整个样本患者分为早期(≤10天)和延迟(>10天)两组。建立了多变量回归模型来检验气管切开术时间与临床结果(包括肺炎、计划外插管、褥疮溃疡、深静脉血栓形成和住院死亡率)之间的关系。结果3545例患者中,43.0%在入院10天内行气管切开术。与Delayed相比,Early通常更年轻(51岁[32-65]vs 58岁[40-77]);P < 0.001)和私人保险(38.6% vs 37.8%, P < 0.001)。调整后,严重的面部损伤和较高的损伤严重程度评分(ISS)与早期气管切开术的几率增加相关。此外,早期气管造口术与肺炎(调整比值比[AOR] 0.70, 95% 0.62-0.82)、褥疮溃疡(AOR 0.61, 95% CI 0.53-0.71)和意外插管(AOR 0.43, 95% CI 0.37-0.49)的发生率降低有关。气管切开术的时机没有改变住院死亡的风险(早期:AOR 1.08, 95% CI 0.86-1.35)。CSCI患者早期气管切开术并发症风险较低,调整死亡率无差异。这些发现表明,早期气管切开术可能改善CSCI患者的急性预后。进一步的前瞻性研究有必要为标准化的护理途径提供信息。
Association of Tracheostomy Timing With Outcomes Following Traumatic Cervical Spinal Cord Injury.
BackgroundPatients with cervical spinal cord injury (CSCI) often require tracheostomy due to a prolonged ventilator dependence. However, optimal time for tracheostomy remains controversial.MethodsAll adult patients (≥18 years) with CSCI who underwent tracheostomy were identified in the 2018-2021 Trauma Quality Improvement Program database. The median time to tracheostomy of the entire sample was found in which patients were categorized into Early (≤10 days) and Delayed (>10 days) cohorts based on whether they were below or above the median. Multivariable regression models were developed to examine the association between tracheostomy timing and clinical outcomes including pneumonia, unplanned intubation, decubitus ulcer, deep vein thrombosis, and in-hospital mortality.ResultsOf 3545 patients, 43.0% underwent tracheostomy within 10 days of admission. Compared to Delayed, Early was more commonly younger (51 [32-65] vs 58 years [40-77]; P < 0.001) and privately insured (38.6 vs 37.8%, P < 0.001). Upon adjustment, severe facial injury and a greater injury severity score (ISS) were associated with increased odds of early tracheostomy. Additionally, early tracheostomy was linked with reduced odds of pneumonia (Adjusted Odds Ratio [AOR] 0.70, 95% 0.62-0.82), decubitus ulcer (AOR 0.61, 95% CI 0.53-0.71), and unplanned intubation (AOR 0.43, 95% CI 0.37-0.49). Tracheostomy timing did not alter risk of in-hospital mortality (Early: AOR 1.08, 95% CI 0.86-1.35).DiscussionEarly tracheostomy in CSCI patients was associated with lower risk of complications, without differences in adjusted mortality rate. These findings suggest that early tracheostomy may improve acute outcomes in CSCI patients. Further prospective research is warranted to inform standardized care pathways.
期刊介绍:
The American Surgeon is a monthly peer-reviewed publication published by the Southeastern Surgical Congress. Its area of concentration is clinical general surgery, as defined by the content areas of the American Board of Surgery: alimentary tract (including bariatric surgery), abdomen and its contents, breast, skin and soft tissue, endocrine system, solid organ transplantation, pediatric surgery, surgical critical care, surgical oncology (including head and neck surgery), trauma and emergency surgery, and vascular surgery.