[多巴胺系统在神经系统疾病中的研究进展]。

Q3 Medicine

生理学报 Pub Date : 2025-04-25 DOI:10.13294/j.aps.2025.0025

Yu-Qi Niu, Jin-Jin Wang, Wen-Fei Cui, Peng Qin, Jian-Feng Gao

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引用次数: 0

摘要

神经系统疾病的病因复杂，对患者造成重大伤害，往往导致预后不良。近年来，多巴胺能系统在神经系统疾病中的作用备受关注，其复杂的调控机制和治疗潜力逐渐被揭示。本文综述了多巴胺能神经元、神经递质多巴胺、多巴胺受体和多巴胺转运体在神经系统疾病（包括阿尔茨海默病、帕金森病和精神分裂症）中的作用，以期进一步阐明疾病机制，为神经系统疾病的治疗提供新的见解和策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Research progress of the dopamine system in neurological diseases].

The etiology of nervous system diseases is complicated, posing significant harm to patients and often resulting in poor prognoses. In recent years, the role of dopaminergic system in nervous system diseases has attracted much attention, and its complex regulatory mechanism and therapeutic potential have been gradually revealed. This paper reviews the role of dopaminergic neurons, the neurotransmitter dopamine, dopamine receptors and dopamine transporters in neurological diseases (including Alzheimer's disease, Parkinson's disease and schizophrenia), with a view to further elucidating the disease mechanism and providing new insights and strategies for the treatment of neurological diseases.

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来源期刊

生理学报 Medicine-Medicine (all)

CiteScore

1.20

自引率

0.00%

发文量

4820

期刊介绍： Acta Physiologica Sinica (APS) is sponsored by the Chinese Association for Physiological Sciences and Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences (CAS), and is published bimonthly by the Science Press, China. APS publishes original research articles in the field of physiology as well as research contributions from other biomedical disciplines and proceedings of conferences and symposia of physiological sciences. Besides “Original Research Articles”, the journal also provides columns as “Brief Review”, “Rapid Communication”, “Experimental Technique”, and “Letter to the Editor”. Articles are published in either Chinese or English according to authors’ submission.