Lei Li , Xulong Fu , Juan Qin, Lianrong Lv, Mengdan Cheng, Biao Wang, Junjie He, Dan Xia, Meng Wang, Haiping Ren, Shike Wang
{"title":"用于MR脊柱图像分割的多初始关注网络","authors":"Lei Li , Xulong Fu , Juan Qin, Lianrong Lv, Mengdan Cheng, Biao Wang, Junjie He, Dan Xia, Meng Wang, Haiping Ren, Shike Wang","doi":"10.1016/j.chemolab.2025.105425","DOIUrl":null,"url":null,"abstract":"<div><div>Accurate segmentation of MR spine images is of great important for the evaluation of spinal diseases. With its unique encoder-decoder symmetric architecture and jump connection design, Unet has become a benchmark model in medical image segmentation since its proposal in 2015. However, the traditional Unet encoder-decoder structure suffers from the problem of semantic information loss during deep feature extraction, and the single-hop connection method is difficult to effectively fuse multi-scale features, resulting in limited segmentation accuracy for complex structures. Responding to these challenges, this study proposes a multi-Inception attention Unet++ (MIAUnet++) model. The model uses different Inception modules to replace the standard convolutional layers of the Unet++, which significantly enhances the multi-scale feature extraction capability by extending the network width and depth. At the same time, multiple attention mechanisms are introduced to further enhance the sensitivity of the network to the boundary information, so that the model can more accurately capture the subtle anatomical structural differences between spine-soft tissues, thus improving the segmentation performance of the network. The experimental results show that the proposed model performs well in the spine image segmentation task with IoU, DSC, TPR and PPV reaching 0.8327, 0.9041, 0.9060 and 0.9068 respectively, outperforming the benchmark method in all metrics. It shows that the proposed method has good performance in MR Spine image segmentation.</div></div>","PeriodicalId":9774,"journal":{"name":"Chemometrics and Intelligent Laboratory Systems","volume":"263 ","pages":"Article 105425"},"PeriodicalIF":3.7000,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"MIAUnet++: Multi-inception attention network for MR spine image segmentation\",\"authors\":\"Lei Li , Xulong Fu , Juan Qin, Lianrong Lv, Mengdan Cheng, Biao Wang, Junjie He, Dan Xia, Meng Wang, Haiping Ren, Shike Wang\",\"doi\":\"10.1016/j.chemolab.2025.105425\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Accurate segmentation of MR spine images is of great important for the evaluation of spinal diseases. With its unique encoder-decoder symmetric architecture and jump connection design, Unet has become a benchmark model in medical image segmentation since its proposal in 2015. However, the traditional Unet encoder-decoder structure suffers from the problem of semantic information loss during deep feature extraction, and the single-hop connection method is difficult to effectively fuse multi-scale features, resulting in limited segmentation accuracy for complex structures. Responding to these challenges, this study proposes a multi-Inception attention Unet++ (MIAUnet++) model. The model uses different Inception modules to replace the standard convolutional layers of the Unet++, which significantly enhances the multi-scale feature extraction capability by extending the network width and depth. At the same time, multiple attention mechanisms are introduced to further enhance the sensitivity of the network to the boundary information, so that the model can more accurately capture the subtle anatomical structural differences between spine-soft tissues, thus improving the segmentation performance of the network. The experimental results show that the proposed model performs well in the spine image segmentation task with IoU, DSC, TPR and PPV reaching 0.8327, 0.9041, 0.9060 and 0.9068 respectively, outperforming the benchmark method in all metrics. It shows that the proposed method has good performance in MR Spine image segmentation.</div></div>\",\"PeriodicalId\":9774,\"journal\":{\"name\":\"Chemometrics and Intelligent Laboratory Systems\",\"volume\":\"263 \",\"pages\":\"Article 105425\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-05-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemometrics and Intelligent Laboratory Systems\",\"FirstCategoryId\":\"94\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0169743925001108\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"AUTOMATION & CONTROL SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemometrics and Intelligent Laboratory Systems","FirstCategoryId":"94","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0169743925001108","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"AUTOMATION & CONTROL SYSTEMS","Score":null,"Total":0}
MIAUnet++: Multi-inception attention network for MR spine image segmentation
Accurate segmentation of MR spine images is of great important for the evaluation of spinal diseases. With its unique encoder-decoder symmetric architecture and jump connection design, Unet has become a benchmark model in medical image segmentation since its proposal in 2015. However, the traditional Unet encoder-decoder structure suffers from the problem of semantic information loss during deep feature extraction, and the single-hop connection method is difficult to effectively fuse multi-scale features, resulting in limited segmentation accuracy for complex structures. Responding to these challenges, this study proposes a multi-Inception attention Unet++ (MIAUnet++) model. The model uses different Inception modules to replace the standard convolutional layers of the Unet++, which significantly enhances the multi-scale feature extraction capability by extending the network width and depth. At the same time, multiple attention mechanisms are introduced to further enhance the sensitivity of the network to the boundary information, so that the model can more accurately capture the subtle anatomical structural differences between spine-soft tissues, thus improving the segmentation performance of the network. The experimental results show that the proposed model performs well in the spine image segmentation task with IoU, DSC, TPR and PPV reaching 0.8327, 0.9041, 0.9060 and 0.9068 respectively, outperforming the benchmark method in all metrics. It shows that the proposed method has good performance in MR Spine image segmentation.
期刊介绍:
Chemometrics and Intelligent Laboratory Systems publishes original research papers, short communications, reviews, tutorials and Original Software Publications reporting on development of novel statistical, mathematical, or computer techniques in Chemistry and related disciplines.
Chemometrics is the chemical discipline that uses mathematical and statistical methods to design or select optimal procedures and experiments, and to provide maximum chemical information by analysing chemical data.
The journal deals with the following topics:
1) Development of new statistical, mathematical and chemometrical methods for Chemistry and related fields (Environmental Chemistry, Biochemistry, Toxicology, System Biology, -Omics, etc.)
2) Novel applications of chemometrics to all branches of Chemistry and related fields (typical domains of interest are: process data analysis, experimental design, data mining, signal processing, supervised modelling, decision making, robust statistics, mixture analysis, multivariate calibration etc.) Routine applications of established chemometrical techniques will not be considered.
3) Development of new software that provides novel tools or truly advances the use of chemometrical methods.
4) Well characterized data sets to test performance for the new methods and software.
The journal complies with International Committee of Medical Journal Editors'' Uniform requirements for manuscripts.