{"title":"无反应物和无抑制剂反应系统的循环和全局吸引子","authors":"Rocco Ascone , Giulia Bernardini , Luca Manzoni","doi":"10.1016/j.tcs.2025.115300","DOIUrl":null,"url":null,"abstract":"<div><div>We explore the computational complexity of deciding the existence of fixed points and cycles that can be reached from any other states (called <em>global attractors</em>) in the dynamics of inhibitorless and reactantless reaction systems. The problems we consider are all known to be <span><math><mtext>PSPACE</mtext></math></span>-complete in the case of unconstrained reaction systems; in this paper, we show that some of them become polynomially solvable when limited to inhibitorless and reactantless reaction systems, while others remain <strong>PSPACE</strong>-complete. Specifically, we prove that the problems of deciding (i) if a given state belongs to a cycle, (ii) whether two reaction systems have at least one cycle in common, and (iii) whether they have the same set of cycles, remain <strong>PSPACE</strong>-complete even in the inhibitorless and reactantless classes, as well as the problem of deciding if a global cycle attractor exists in a reactantless reaction system. Interestingly, however, we demonstrate that no global cycle attractor of length at least 2 can exist in inhibitorless reaction systems; and no global cycle attractor of length greater than 2 can exist in reactantless reaction systems. Furthermore, we show that the problems of deciding whether a given state is a global attractor and whether a global fixed point attractor exists become polynomially solvable when restricted to inhibitorless and reactantless reaction systems.</div></div>","PeriodicalId":49438,"journal":{"name":"Theoretical Computer Science","volume":"1045 ","pages":"Article 115300"},"PeriodicalIF":1.0000,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cycles and global attractors of reactantless and inhibitorless reaction systems\",\"authors\":\"Rocco Ascone , Giulia Bernardini , Luca Manzoni\",\"doi\":\"10.1016/j.tcs.2025.115300\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We explore the computational complexity of deciding the existence of fixed points and cycles that can be reached from any other states (called <em>global attractors</em>) in the dynamics of inhibitorless and reactantless reaction systems. The problems we consider are all known to be <span><math><mtext>PSPACE</mtext></math></span>-complete in the case of unconstrained reaction systems; in this paper, we show that some of them become polynomially solvable when limited to inhibitorless and reactantless reaction systems, while others remain <strong>PSPACE</strong>-complete. Specifically, we prove that the problems of deciding (i) if a given state belongs to a cycle, (ii) whether two reaction systems have at least one cycle in common, and (iii) whether they have the same set of cycles, remain <strong>PSPACE</strong>-complete even in the inhibitorless and reactantless classes, as well as the problem of deciding if a global cycle attractor exists in a reactantless reaction system. Interestingly, however, we demonstrate that no global cycle attractor of length at least 2 can exist in inhibitorless reaction systems; and no global cycle attractor of length greater than 2 can exist in reactantless reaction systems. Furthermore, we show that the problems of deciding whether a given state is a global attractor and whether a global fixed point attractor exists become polynomially solvable when restricted to inhibitorless and reactantless reaction systems.</div></div>\",\"PeriodicalId\":49438,\"journal\":{\"name\":\"Theoretical Computer Science\",\"volume\":\"1045 \",\"pages\":\"Article 115300\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-05-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Theoretical Computer Science\",\"FirstCategoryId\":\"94\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0304397525002385\",\"RegionNum\":4,\"RegionCategory\":\"计算机科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"COMPUTER SCIENCE, THEORY & METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Theoretical Computer Science","FirstCategoryId":"94","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0304397525002385","RegionNum":4,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"COMPUTER SCIENCE, THEORY & METHODS","Score":null,"Total":0}
Cycles and global attractors of reactantless and inhibitorless reaction systems
We explore the computational complexity of deciding the existence of fixed points and cycles that can be reached from any other states (called global attractors) in the dynamics of inhibitorless and reactantless reaction systems. The problems we consider are all known to be -complete in the case of unconstrained reaction systems; in this paper, we show that some of them become polynomially solvable when limited to inhibitorless and reactantless reaction systems, while others remain PSPACE-complete. Specifically, we prove that the problems of deciding (i) if a given state belongs to a cycle, (ii) whether two reaction systems have at least one cycle in common, and (iii) whether they have the same set of cycles, remain PSPACE-complete even in the inhibitorless and reactantless classes, as well as the problem of deciding if a global cycle attractor exists in a reactantless reaction system. Interestingly, however, we demonstrate that no global cycle attractor of length at least 2 can exist in inhibitorless reaction systems; and no global cycle attractor of length greater than 2 can exist in reactantless reaction systems. Furthermore, we show that the problems of deciding whether a given state is a global attractor and whether a global fixed point attractor exists become polynomially solvable when restricted to inhibitorless and reactantless reaction systems.
期刊介绍:
Theoretical Computer Science is mathematical and abstract in spirit, but it derives its motivation from practical and everyday computation. Its aim is to understand the nature of computation and, as a consequence of this understanding, provide more efficient methodologies. All papers introducing or studying mathematical, logic and formal concepts and methods are welcome, provided that their motivation is clearly drawn from the field of computing.