成釉细胞瘤:回顾性单机构研究与分析86例

Pengleang Cheang , Amit Dattani , Lykheang Lou , Sandeth Phan
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引用次数: 0

摘要

本研究的目的是调查6年期间(2018年1月至2023年12月)在柬埔寨一家研究所治疗成釉细胞瘤的结果。一项回顾性研究旨在纳入所有被诊断为成釉细胞瘤并在柬埔寨金边Preah Ang Duong医院口腔颌面外科接受治疗的患者。利用患者病历和组织病理学数据库,整理患者的人口统计学细节、病变位置和大小、病变亚型的组织学分类、影像学表现、治疗和5年复发率。86名患者被纳入研究。75例(87.2%)位于下颌骨,38例(44.2%)患者的成釉细胞瘤最常见的大小为3.1 ~ 6cm。根据2022年WHO成釉细胞瘤分类,55例(64%)患者报告了常规成釉细胞瘤。11例患者(13%)接受了有袋化手术,9例患者(60%)在2年内复发。10例患者(12%)接受了去核手术,6例患者在3年内复发。46例(53%)行根治性手术,6例5年内复发。19例患者(22%)拒绝治疗。总体而言,接受治疗的患者中有15/67(22.3%)出现某种形式的复发,其中根治性切除的复发率最低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ameloblastoma: Retrospective single institute study and analysis of 86 subjects
The aim of this study was to investigate the results of ameloblastoma treated at a single Cambodian institute during a 6-year period (Jan 2018–Dec 2023). A retrospective study was designed to include all patients who had been diagnosed with ameloblastoma and treated at the Department of Oral and Maxillofacial Surgery, Preah Ang Duong Hospital, Phnom Penh, Cambodia. Demographic details, location and size of lesion, histological classification of lesion by subtype, radiographic appearance, treatment and recurrence rates for up to 5 years were collated by using patients’ records and the histopathology database. 86 patients were included in the study. 75 (87.2 %) were located in the mandible, the most common size of ameloblastoma at presentation was 3.1–6 cm in 38 patients (44.2 %). By the 2022 WHO Classification of ameloblastomas, conventional ameloblastomas were reported in 55 patients (64 %). 11 patients (13 %) underwent marsupialization with 9 patients (60 %) having a recurrence within 2 years. 10 patients (12 %) underwent enucleation with 6 patients having recurrence within 3 years. 46 patients (53 %) underwent radical resection with 6 patients having recurrence within 5 years. 19 patients (22 %) declined treatment. Overall, 15/67 treated patients (22.3 %) had some form of recurrence in which radical resection had the lowest rate of recurrence.
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