腹腔镜裂孔疝修补术和前180°部分基底部复盖术治疗症状性裂孔疝后的生活质量

IF 0.9 Q4 ORTHOPEDICS
Sze Li Siow, Ernest Cun Wang Ong
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引用次数: 0

摘要

背景腹腔镜裂孔疝修补术(LHHR)是治疗有症状的裂孔疝的首选方法。本研究评估LHHR合并前180°部分眼底塌陷后的健康相关生活质量(HRQOL)结果。方法2020年6月至2022年12月,连续40例LHHR患者行前180°部分眼底复制。患者根据以下标准之一被纳入:尽管有最佳药物治疗,但症状仍持续存在(55%),倾向于手术解决方案而不是终身药物治疗(37.5%),或并发症包括反流性食管炎/巴雷特食管(7.5%)。术前、术后1、6、12个月采用SF-36问卷评估HRQOL。结果12个月时,患者身体功能(66.3±24.7至95.6±7.7,p < 0.001)、身体疼痛(38.1±28.1至79.2±18.6,p < 0.001)、一般健康(37.7±16.2至66.1±23.6,p < 0.001)、社会功能(62.5±23.7至85.6±16.1,p < 0.001)、心理健康(68.2±21.4至83.7±12.5,p < 0.001)均有显著改善。身体健康导致的角色限制逐渐改善,在12个月时变得显著(60.0±45.6至86.9±16.8,p < 0.001)。活力的早期改善(p = 0.02)和由于情绪健康造成的角色限制(p = 0.331)在12个月后有所下降。中位住院时间为3天,无重大并发症。1年后,72.5%的患者无药物治疗,7.5%的患者解剖性复发。复发患者的身体功能(82.3比96.8,p = 0.02)和身体疼痛评分(65.7比80.5,p = 0.04)较低,但与基线相比仍有显著改善。体重指数、受教育程度、年龄和缺陷面积对结果没有影响(均p >; 0.05)。结论LHHR合并前180°部分眼底复制可显著改善患者在多个领域的生活质量,并在术后12个月持续改善,尤其是在身体功能、疼痛和社交功能方面。大多数区域在12个月后达到或超过了人口标准,确立了这种方法作为症状性滑脱裂孔疝的有效治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quality of Life Following Laparoscopic Hiatal Hernia Repair and Anterior 180° Partial Fundoplication for Symptomatic Sliding Hiatal Hernia

Background

Laparoscopic hiatal hernia repair (LHHR) is the treatment of choice for symptomatic sliding hiatal hernia. This study evaluates health-related quality of life (HRQOL) outcomes following LHHR with anterior 180° partial fundoplication.

Methods

Forty consecutive patients underwent LHHR with anterior 180° partial fundoplication between June 2020 and December 2022. Patients were included based on one of the following criteria: persistent symptoms despite optimal medical therapy (55%), preference for a surgical solution over lifelong medication (37.5%), or complications including reflux oesophagitis/Barrett's esophagus (7.5%). HRQOL was assessed using the SF-36 questionnaire preoperatively and at 1, 6, and 12 months postoperatively.

Results

Significant improvements were observed in physical functioning (66.3 ± 24.7 to 95.6 ± 7.7, p < 0.001), bodily pain (38.1 ± 28.1 to 79.2 ± 18.6, p < 0.001), general health (37.7 ± 16.2 to 66.1 ± 23.6, p < 0.001), social function (62.5 ± 23.7 to 85.6 ± 16.1, p < 0.001), and mental health (68.2 ± 21.4 to 83.7 ± 12.5, p < 0.001) at 12 months. Role limitations due to physical health improved gradually, becoming significant at 12 months (60.0 ± 45.6 to 86.9 ± 16.8, p < 0.001). Early improvements in vitality (p = 0.02) and role limitations due to emotional health (p = 0.331) showed some decline by 12 months. The median hospital stay was 3 days, with no major complications. At 1 year, 72.5% of patients were medication-free, while anatomical recurrence was observed in 7.5%. Patients with recurrence showed lower physical functioning (82.3 vs. 96.8, p = 0.02) and bodily pain scores (65.7 vs. 80.5, p = 0.04) but still demonstrated significant improvement from baseline. Body mass index, education level, age, and defect area did not influence outcomes (all p > 0.05).

Conclusion

LHHR with anterior 180° partial fundoplication significantly improves quality of life across multiple domains, with sustained benefits at 12 months post-surgery, particularly in physical function, pain, and social functioning. Most domains reached or surpassed population norms by 12 months, establishing this approach as an effective treatment for symptomatic sliding hiatal hernia.

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