Reaction of 1-Antipyryl-4-aroyl-5-methoxycarbonyl-1H-pyrrole-2,3-diones with N-Substituted and N-Unsubstituted 3-Amino-5,5-dimethylcyclohex-2-en-1-ones

Nucleophilic transformations of N-antipyryl-substituted 1H-pyrrole-2,3-diones by the action of enamines derived from dimedone as 1,3-C,N-binucleophiles afforded 1′-antipyryl-3′-aroyl-4′-hydroxy-6,6-dimethyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-triones and 1′-antipyryl-1-aryl-3′-aroyl-4′-hydroxy-6,6-dimethyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-triones.