4-氯-2,6-双（1h -咪唑-2-基）吡啶的合成

IF 0.9 4区化学 Q4 CHEMISTRY, ORGANIC

Russian Journal of Organic Chemistry Pub Date : 2025-05-07 DOI:10.1134/S1070428024604801

I. A. Osʼkina, L. G. Lavrenova, A. Ya. Tikhonov

引用次数: 0

摘要

将Chelidamic acid依次转化为4-氯吡啶-2,6-二甲酰胺和4-氯吡啶-2,6-二腈，后者与2-氨基乙醛二乙基缩醛反应得到4-氯-2,6-二（1 -咪唑-2-基）吡啶，这是一种很有前途的三齿配体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Synthesis of 4-Chloro-2,6-bis(1H-imidazol-2-yl)pyridine

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Synthesis of 4-Chloro-2,6-bis(1H-imidazol-2-yl)pyridine

Chelidamic acid was successively converted to 4-chloropyridine-2,6-dicarboxamide and 4-chloropyridine-2,6-dicarbonitrile, and reaction of the latter with 2-aminoacetaldehyde diethyl acetal afforded 4-chloro-2,6-bis(1H-imidazol-2-yl)pyridine which is a promising tridentate ligand.

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来源期刊

Russian Journal of Organic Chemistry 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

139

审稿时长

3-6 weeks

期刊介绍： Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.