确保药品可追溯性:区块链增强的隐私保护和药品供应链中的防伪措施

IF 2.7 4区 医学 Q2 PHARMACOLOGY & PHARMACY
R. Kalpana, S. Sridevi
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引用次数: 0

摘要

制药行业在确保药品的真实性和保护整个供应链的敏感信息方面面临着严重的威胁。传统的安全措施往往无法全面解决这些问题,导致假冒药品和非法获取数据等弱点。目的本研究提出了一种集成的、最先进的安全系统,以提供更好的数据保护、加密有效性和制药行业供应链的完整性。建议的框架将基于属性的加密(ABE)与QR码技术相结合,用于安全、细粒度的数据加密。针对加密密钥选择的优化问题,提出了一种结合小熊猫优化算法(RPO)和群体教学优化算法(GTOA)的混合优化方法。此外,使用多方计算(MPC)协议和Shamir的秘密共享方案来保证只有合法的各方才能重建和查看重要数据,保持机密性和完整性。结果性能测试表明,该框架的性能优于传统的加密算法。注册的加密时间为0.21234秒,比RSA(0.308372)和3DES(0.36462)快。解密耗时0.22112秒,比RSA的0.312773秒要快。总周转时间缩短至0.431231秒,远远优于Blowfish的0.52356秒。该系统的恢复效率水平为0.987453,高于RSA的0.92133和Blowfish的0.94109。结论该安全模型为药品供应链端到端数据保护、防止篡改和非法访问提供了安全可行的解决方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Securing Drug Traceability: Blockchain-Enhanced Privacy Protection and Anti-Counterfeit Measures in Pharmaceutical Supply Chains

Background

The pharmaceutical sector is under severe threat in ensuring the genuineness of drugs and securing sensitive information throughout the supply chain. Conventional security measures tend to be ineffective in addressing these issues comprehensively, resulting in weaknesses like counterfeit medicines and illegitimate access to data.

Objective

This research suggests an integrated, state-of-the-art security system to provide improved data protection, encryption effectiveness, and supply chain integrity in the pharmaceutical industry.

Methods

The suggested framework utilizes Attribute-Based Encryption (ABE) in conjunction with QR code technology for secure, fine-grained data encryption. For the optimization of encryption key selection, a hybrid optimization method combining Red Panda Optimization (RPO) Algorithm and Group Teaching Optimization Algorithm (GTOA) is proposed. Additionally, Multi-Party Computation (MPC) protocols and Shamir’s Secret Sharing scheme are used to guarantee that only legitimate parties can reconstruct and view important data, maintaining confidentiality and integrity.

Results

Performance testing shows that the framework proposed performs better than traditional cryptos. Encryption time registered was at 0.21234 seconds, which was quicker than RSA (0.308372) and 3DES (0.36462). Decryption took 0.22112 seconds, which was faster than RSA’s 0.312773. Total turnaround time was cut to 0.431231 seconds, which was far superior to Blowfish at 0.52356 seconds. The system also attained a restoration efficiency level of 0.987453, ahead of RSA at 0.92133 and Blowfish at 0.94109.

Conclusion

The security model offers a secure and feasible solution for end-to-end data protection and prevention of tampering and unauthorized access in the pharma supply chain.

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来源期刊
Journal of Pharmaceutical Innovation
Journal of Pharmaceutical Innovation PHARMACOLOGY & PHARMACY-
CiteScore
3.70
自引率
3.80%
发文量
90
审稿时长
>12 weeks
期刊介绍: The Journal of Pharmaceutical Innovation (JPI), is an international, multidisciplinary peer-reviewed scientific journal dedicated to publishing high quality papers emphasizing innovative research and applied technologies within the pharmaceutical and biotechnology industries. JPI''s goal is to be the premier communication vehicle for the critical body of knowledge that is needed for scientific evolution and technical innovation, from R&D to market. Topics will fall under the following categories: Materials science, Product design, Process design, optimization, automation and control, Facilities; Information management, Regulatory policy and strategy, Supply chain developments , Education and professional development, Journal of Pharmaceutical Innovation publishes four issues a year.
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