{"title":"确保药品可追溯性:区块链增强的隐私保护和药品供应链中的防伪措施","authors":"R. Kalpana, S. Sridevi","doi":"10.1007/s12247-025-09964-9","DOIUrl":null,"url":null,"abstract":"<div><h3>\n <b>Background</b>\n </h3><p>The pharmaceutical sector is under severe threat in ensuring the genuineness of drugs and securing sensitive information throughout the supply chain. Conventional security measures tend to be ineffective in addressing these issues comprehensively, resulting in weaknesses like counterfeit medicines and illegitimate access to data.</p><h3>\n <b>Objective</b>\n </h3><p>This research suggests an integrated, state-of-the-art security system to provide improved data protection, encryption effectiveness, and supply chain integrity in the pharmaceutical industry.</p><h3>\n <b>Methods</b>\n </h3><p>The suggested framework utilizes Attribute-Based Encryption (ABE) in conjunction with QR code technology for secure, fine-grained data encryption. For the optimization of encryption key selection, a hybrid optimization method combining Red Panda Optimization (RPO) Algorithm and Group Teaching Optimization Algorithm (GTOA) is proposed. Additionally, Multi-Party Computation (MPC) protocols and Shamir’s Secret Sharing scheme are used to guarantee that only legitimate parties can reconstruct and view important data, maintaining confidentiality and integrity.</p><h3>\n <b>Results</b>\n </h3><p>Performance testing shows that the framework proposed performs better than traditional cryptos. Encryption time registered was at 0.21234 seconds, which was quicker than RSA (0.308372) and 3DES (0.36462). Decryption took 0.22112 seconds, which was faster than RSA’s 0.312773. Total turnaround time was cut to 0.431231 seconds, which was far superior to Blowfish at 0.52356 seconds. The system also attained a restoration efficiency level of 0.987453, ahead of RSA at 0.92133 and Blowfish at 0.94109.</p><h3>\n <b>Conclusion</b>\n </h3><p>The security model offers a secure and feasible solution for end-to-end data protection and prevention of tampering and unauthorized access in the pharma supply chain.</p></div>","PeriodicalId":656,"journal":{"name":"Journal of Pharmaceutical Innovation","volume":"20 3","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Securing Drug Traceability: Blockchain-Enhanced Privacy Protection and Anti-Counterfeit Measures in Pharmaceutical Supply Chains\",\"authors\":\"R. Kalpana, S. Sridevi\",\"doi\":\"10.1007/s12247-025-09964-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>\\n <b>Background</b>\\n </h3><p>The pharmaceutical sector is under severe threat in ensuring the genuineness of drugs and securing sensitive information throughout the supply chain. Conventional security measures tend to be ineffective in addressing these issues comprehensively, resulting in weaknesses like counterfeit medicines and illegitimate access to data.</p><h3>\\n <b>Objective</b>\\n </h3><p>This research suggests an integrated, state-of-the-art security system to provide improved data protection, encryption effectiveness, and supply chain integrity in the pharmaceutical industry.</p><h3>\\n <b>Methods</b>\\n </h3><p>The suggested framework utilizes Attribute-Based Encryption (ABE) in conjunction with QR code technology for secure, fine-grained data encryption. For the optimization of encryption key selection, a hybrid optimization method combining Red Panda Optimization (RPO) Algorithm and Group Teaching Optimization Algorithm (GTOA) is proposed. Additionally, Multi-Party Computation (MPC) protocols and Shamir’s Secret Sharing scheme are used to guarantee that only legitimate parties can reconstruct and view important data, maintaining confidentiality and integrity.</p><h3>\\n <b>Results</b>\\n </h3><p>Performance testing shows that the framework proposed performs better than traditional cryptos. Encryption time registered was at 0.21234 seconds, which was quicker than RSA (0.308372) and 3DES (0.36462). Decryption took 0.22112 seconds, which was faster than RSA’s 0.312773. Total turnaround time was cut to 0.431231 seconds, which was far superior to Blowfish at 0.52356 seconds. The system also attained a restoration efficiency level of 0.987453, ahead of RSA at 0.92133 and Blowfish at 0.94109.</p><h3>\\n <b>Conclusion</b>\\n </h3><p>The security model offers a secure and feasible solution for end-to-end data protection and prevention of tampering and unauthorized access in the pharma supply chain.</p></div>\",\"PeriodicalId\":656,\"journal\":{\"name\":\"Journal of Pharmaceutical Innovation\",\"volume\":\"20 3\",\"pages\":\"\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-05-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmaceutical Innovation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s12247-025-09964-9\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmaceutical Innovation","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s12247-025-09964-9","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Securing Drug Traceability: Blockchain-Enhanced Privacy Protection and Anti-Counterfeit Measures in Pharmaceutical Supply Chains
Background
The pharmaceutical sector is under severe threat in ensuring the genuineness of drugs and securing sensitive information throughout the supply chain. Conventional security measures tend to be ineffective in addressing these issues comprehensively, resulting in weaknesses like counterfeit medicines and illegitimate access to data.
Objective
This research suggests an integrated, state-of-the-art security system to provide improved data protection, encryption effectiveness, and supply chain integrity in the pharmaceutical industry.
Methods
The suggested framework utilizes Attribute-Based Encryption (ABE) in conjunction with QR code technology for secure, fine-grained data encryption. For the optimization of encryption key selection, a hybrid optimization method combining Red Panda Optimization (RPO) Algorithm and Group Teaching Optimization Algorithm (GTOA) is proposed. Additionally, Multi-Party Computation (MPC) protocols and Shamir’s Secret Sharing scheme are used to guarantee that only legitimate parties can reconstruct and view important data, maintaining confidentiality and integrity.
Results
Performance testing shows that the framework proposed performs better than traditional cryptos. Encryption time registered was at 0.21234 seconds, which was quicker than RSA (0.308372) and 3DES (0.36462). Decryption took 0.22112 seconds, which was faster than RSA’s 0.312773. Total turnaround time was cut to 0.431231 seconds, which was far superior to Blowfish at 0.52356 seconds. The system also attained a restoration efficiency level of 0.987453, ahead of RSA at 0.92133 and Blowfish at 0.94109.
Conclusion
The security model offers a secure and feasible solution for end-to-end data protection and prevention of tampering and unauthorized access in the pharma supply chain.
期刊介绍:
The Journal of Pharmaceutical Innovation (JPI), is an international, multidisciplinary peer-reviewed scientific journal dedicated to publishing high quality papers emphasizing innovative research and applied technologies within the pharmaceutical and biotechnology industries. JPI''s goal is to be the premier communication vehicle for the critical body of knowledge that is needed for scientific evolution and technical innovation, from R&D to market. Topics will fall under the following categories:
Materials science,
Product design,
Process design, optimization, automation and control,
Facilities; Information management,
Regulatory policy and strategy,
Supply chain developments ,
Education and professional development,
Journal of Pharmaceutical Innovation publishes four issues a year.