Andrew C. Kidd , Alex Vesey , Saurabh Vohra , Agata Kochman , Sharon Armstrong
{"title":"复发性骨肉瘤并发腹主动脉肿瘤血栓致急性动脉闭塞1例","authors":"Andrew C. Kidd , Alex Vesey , Saurabh Vohra , Agata Kochman , Sharon Armstrong","doi":"10.1016/j.rcro.2025.100344","DOIUrl":null,"url":null,"abstract":"<div><div>We describe a 21-year-old male patient with a history of relapsed osteosarcoma who presented with symptoms consistent with acute right lower limb ischaemia. He had received 7 cycles of palliative Regorafenib 160 mg once daily. Imaging demonstrated an occluded abdominal aorta. Histopathology of a resected thrombus cast revealed metastatic tumour-thrombus. Re-perfusion of his lower limb was achieved. This case report emphasises the importance of inter-professional collaboration in managing patients with rare cancers who present as an emergency. To our knowledge, this is the first case reporting an arterial tumour-thrombus in a patient with relapsed osteosarcoma.</div></div>","PeriodicalId":101248,"journal":{"name":"The Royal College of Radiologists Open","volume":"3 ","pages":"Article 100344"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Acute arterial occlusion due to abdominal aortic tumour-thrombus in relapsed osteosarcoma: A case report\",\"authors\":\"Andrew C. Kidd , Alex Vesey , Saurabh Vohra , Agata Kochman , Sharon Armstrong\",\"doi\":\"10.1016/j.rcro.2025.100344\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We describe a 21-year-old male patient with a history of relapsed osteosarcoma who presented with symptoms consistent with acute right lower limb ischaemia. He had received 7 cycles of palliative Regorafenib 160 mg once daily. Imaging demonstrated an occluded abdominal aorta. Histopathology of a resected thrombus cast revealed metastatic tumour-thrombus. Re-perfusion of his lower limb was achieved. This case report emphasises the importance of inter-professional collaboration in managing patients with rare cancers who present as an emergency. To our knowledge, this is the first case reporting an arterial tumour-thrombus in a patient with relapsed osteosarcoma.</div></div>\",\"PeriodicalId\":101248,\"journal\":{\"name\":\"The Royal College of Radiologists Open\",\"volume\":\"3 \",\"pages\":\"Article 100344\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Royal College of Radiologists Open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S277306622500110X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Royal College of Radiologists Open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S277306622500110X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Acute arterial occlusion due to abdominal aortic tumour-thrombus in relapsed osteosarcoma: A case report
We describe a 21-year-old male patient with a history of relapsed osteosarcoma who presented with symptoms consistent with acute right lower limb ischaemia. He had received 7 cycles of palliative Regorafenib 160 mg once daily. Imaging demonstrated an occluded abdominal aorta. Histopathology of a resected thrombus cast revealed metastatic tumour-thrombus. Re-perfusion of his lower limb was achieved. This case report emphasises the importance of inter-professional collaboration in managing patients with rare cancers who present as an emergency. To our knowledge, this is the first case reporting an arterial tumour-thrombus in a patient with relapsed osteosarcoma.