Frederico Schmitt Kremer, João Pedro Gomes Greco, Elias Eduardo Barbosa da Rosa
{"title":"BRS:一种检测移动元件中杀菌剂耐药性的工具","authors":"Frederico Schmitt Kremer, João Pedro Gomes Greco, Elias Eduardo Barbosa da Rosa","doi":"10.1016/j.simpa.2025.100758","DOIUrl":null,"url":null,"abstract":"<div><div>Biocides play a critical role in controlling microorganisms, yet their widespread use has contributed to the emergence of bacterial resistance, often linked to antibiotic cross-resistance. Multidrug-resistant pathogens pose a growing public health concern due to their adaptability and presence in various environments, including hospitals. Previously, our group developed the Biocide Resistance Scanner (BRS), a bioinformatics pipeline designed to identify biocide resistance genes in the mobilome of ESKAPE strains isolated in Brazil. Now, we detail the implementation of BRS and extend its application to the analysis of the pathogen <em>Campylobacter jejuni</em>.</div></div>","PeriodicalId":29771,"journal":{"name":"Software Impacts","volume":"24 ","pages":"Article 100758"},"PeriodicalIF":1.3000,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"BRS: A tool for detecting biocide resistance in mobile elements\",\"authors\":\"Frederico Schmitt Kremer, João Pedro Gomes Greco, Elias Eduardo Barbosa da Rosa\",\"doi\":\"10.1016/j.simpa.2025.100758\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Biocides play a critical role in controlling microorganisms, yet their widespread use has contributed to the emergence of bacterial resistance, often linked to antibiotic cross-resistance. Multidrug-resistant pathogens pose a growing public health concern due to their adaptability and presence in various environments, including hospitals. Previously, our group developed the Biocide Resistance Scanner (BRS), a bioinformatics pipeline designed to identify biocide resistance genes in the mobilome of ESKAPE strains isolated in Brazil. Now, we detail the implementation of BRS and extend its application to the analysis of the pathogen <em>Campylobacter jejuni</em>.</div></div>\",\"PeriodicalId\":29771,\"journal\":{\"name\":\"Software Impacts\",\"volume\":\"24 \",\"pages\":\"Article 100758\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Software Impacts\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2665963825000181\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"COMPUTER SCIENCE, SOFTWARE ENGINEERING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Software Impacts","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2665963825000181","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"COMPUTER SCIENCE, SOFTWARE ENGINEERING","Score":null,"Total":0}
BRS: A tool for detecting biocide resistance in mobile elements
Biocides play a critical role in controlling microorganisms, yet their widespread use has contributed to the emergence of bacterial resistance, often linked to antibiotic cross-resistance. Multidrug-resistant pathogens pose a growing public health concern due to their adaptability and presence in various environments, including hospitals. Previously, our group developed the Biocide Resistance Scanner (BRS), a bioinformatics pipeline designed to identify biocide resistance genes in the mobilome of ESKAPE strains isolated in Brazil. Now, we detail the implementation of BRS and extend its application to the analysis of the pathogen Campylobacter jejuni.