Nick Trott, William Holland, Olivia Hoffmann, Mohamed G. Shiha, Suneil A. Raju, Hugo A. Penny, Kevin Whelan, David S. Sanders
{"title":"乳糜泻患者的食物相关生活质量及其与人口学和临床特征的关系","authors":"Nick Trott, William Holland, Olivia Hoffmann, Mohamed G. Shiha, Suneil A. Raju, Hugo A. Penny, Kevin Whelan, David S. Sanders","doi":"10.1111/jhn.70051","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Coeliac disease is an autoimmune disorder resulting from the consumption of gluten in genetically susceptible individuals. Current treatment is a lifelong gluten-free diet that significantly affects quality of life. Food-related quality of life (FRQoL) refers to the impact of food, nutrition, eating and drinking on the psychosocial aspects of life. The aim of this study was to examine FRQoL in patients with coeliac disease.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Patients with confirmed coeliac disease completed the validated FR-QoL-29 questionnaire adapted for coeliac disease (FR-QoL-29-Coeliac) and provided demographic and clinical information.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Questionnaires were completed by 138 adults (62% female, mean age 52.3 SD ± 18.6). FR-QoL-29 scores were mean 85.8 (SD ± 23.1). The lowest FR-QoL-29 scores were in the 18–35 year age group (76.6 ± 17.2) compared with the highest in the 56+ age group (92.5 ± 22.3, <i>p</i> = 0.002). Patients with ≥ 4 gastrointestinal (GiS) symptoms had significantly lower FR-QoL-29 scores (77.9 ± 20.7) compared with those with 1–3 GiS (96.7 ± 21, <i>p</i> = 0.0001).</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>FRQoL is impaired in coeliac disease and is particularly lower in younger people and those with greater GI symptom burden. Further research should examine the mechanisms that reduce FRQoL in coeliac disease to identify interventions that minimise the burden for patients.</p>\n </section>\n </div>","PeriodicalId":54803,"journal":{"name":"Journal of Human Nutrition and Dietetics","volume":"38 3","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Food Related Quality of Life and Associations With Demographic and Clinical Characteristics in People With Coeliac Disease\",\"authors\":\"Nick Trott, William Holland, Olivia Hoffmann, Mohamed G. Shiha, Suneil A. Raju, Hugo A. Penny, Kevin Whelan, David S. Sanders\",\"doi\":\"10.1111/jhn.70051\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Coeliac disease is an autoimmune disorder resulting from the consumption of gluten in genetically susceptible individuals. Current treatment is a lifelong gluten-free diet that significantly affects quality of life. Food-related quality of life (FRQoL) refers to the impact of food, nutrition, eating and drinking on the psychosocial aspects of life. The aim of this study was to examine FRQoL in patients with coeliac disease.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Patients with confirmed coeliac disease completed the validated FR-QoL-29 questionnaire adapted for coeliac disease (FR-QoL-29-Coeliac) and provided demographic and clinical information.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Questionnaires were completed by 138 adults (62% female, mean age 52.3 SD ± 18.6). FR-QoL-29 scores were mean 85.8 (SD ± 23.1). The lowest FR-QoL-29 scores were in the 18–35 year age group (76.6 ± 17.2) compared with the highest in the 56+ age group (92.5 ± 22.3, <i>p</i> = 0.002). Patients with ≥ 4 gastrointestinal (GiS) symptoms had significantly lower FR-QoL-29 scores (77.9 ± 20.7) compared with those with 1–3 GiS (96.7 ± 21, <i>p</i> = 0.0001).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>FRQoL is impaired in coeliac disease and is particularly lower in younger people and those with greater GI symptom burden. Further research should examine the mechanisms that reduce FRQoL in coeliac disease to identify interventions that minimise the burden for patients.</p>\\n </section>\\n </div>\",\"PeriodicalId\":54803,\"journal\":{\"name\":\"Journal of Human Nutrition and Dietetics\",\"volume\":\"38 3\",\"pages\":\"\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-04-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Human Nutrition and Dietetics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/jhn.70051\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Human Nutrition and Dietetics","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jhn.70051","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
Food Related Quality of Life and Associations With Demographic and Clinical Characteristics in People With Coeliac Disease
Background
Coeliac disease is an autoimmune disorder resulting from the consumption of gluten in genetically susceptible individuals. Current treatment is a lifelong gluten-free diet that significantly affects quality of life. Food-related quality of life (FRQoL) refers to the impact of food, nutrition, eating and drinking on the psychosocial aspects of life. The aim of this study was to examine FRQoL in patients with coeliac disease.
Methods
Patients with confirmed coeliac disease completed the validated FR-QoL-29 questionnaire adapted for coeliac disease (FR-QoL-29-Coeliac) and provided demographic and clinical information.
Results
Questionnaires were completed by 138 adults (62% female, mean age 52.3 SD ± 18.6). FR-QoL-29 scores were mean 85.8 (SD ± 23.1). The lowest FR-QoL-29 scores were in the 18–35 year age group (76.6 ± 17.2) compared with the highest in the 56+ age group (92.5 ± 22.3, p = 0.002). Patients with ≥ 4 gastrointestinal (GiS) symptoms had significantly lower FR-QoL-29 scores (77.9 ± 20.7) compared with those with 1–3 GiS (96.7 ± 21, p = 0.0001).
Conclusions
FRQoL is impaired in coeliac disease and is particularly lower in younger people and those with greater GI symptom burden. Further research should examine the mechanisms that reduce FRQoL in coeliac disease to identify interventions that minimise the burden for patients.
期刊介绍：
Journal of Human Nutrition and Dietetics is an international peer-reviewed journal publishing papers in applied nutrition and dietetics. Papers are therefore welcomed on:
- Clinical nutrition and the practice of therapeutic dietetics
- Clinical and professional guidelines
- Public health nutrition and nutritional epidemiology
- Dietary surveys and dietary assessment methodology
- Health promotion and intervention studies and their effectiveness
- Obesity, weight control and body composition
- Research on psychological determinants of healthy and unhealthy eating behaviour. Focus can for example be on attitudes, brain correlates of food reward processing, social influences, impulsivity, cognitive control, cognitive processes, dieting, psychological treatments.
- Appetite, Food intake and nutritional status
- Nutrigenomics and molecular nutrition
- The journal does not publish animal research
The journal is published in an online-only format. No printed issue of this title will be produced but authors will still be able to order offprints of their own articles.
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