{"title":"当雷诺现象伴随着可怕的数字溃疡时:两例报告","authors":"Karen Vergara MD","doi":"10.1016/j.rmclc.2025.03.002","DOIUrl":null,"url":null,"abstract":"<div><div>Raynaud's phenomenon (RP) is a vasospastic disorder, often triggered by cold or stress, that causes changes in the color of the fingers due to excessive vasoconstriction. A prevalence ranging from 5% to 14.5% has been described. Between 5% and 10% of patients with RP develop autoimmune diseases, such as systemic sclerosis, systemic lupus erythematosus, or rheumatoid arthritis. Of relevance, approximately 50% of patients with systemic sclerosis and RP experience digital ulcers, which can cause considerable pain and functional impairment.</div><div>The clinical cases described in this article correspond to a 33-year-old woman and an 18-year-old man with RP and digital ulcers. The woman showed no improvement despite medical treatment, while the man experienced healing of his lesions.</div><div>The pathophysiology of RF involves genetic and environmental factors, and the management of digital ulcers requires a multidisciplinary approach, combining medical care with wound care and the use of vasodilators. Although rare, digital ulcers represent a significant challenge that needs further research and better treatment options.</div><div>The aim of this paper is to describe the clinical features, laboratory, complementary studies, treatment and evolution of two patients with digital ulcers.</div></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"36 2","pages":"Pages 88-92"},"PeriodicalIF":0.2000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cuando el fenómeno de Raynaud se acompaña de las temidas úlceras digitales: reporte de dos casos\",\"authors\":\"Karen Vergara MD\",\"doi\":\"10.1016/j.rmclc.2025.03.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Raynaud's phenomenon (RP) is a vasospastic disorder, often triggered by cold or stress, that causes changes in the color of the fingers due to excessive vasoconstriction. A prevalence ranging from 5% to 14.5% has been described. Between 5% and 10% of patients with RP develop autoimmune diseases, such as systemic sclerosis, systemic lupus erythematosus, or rheumatoid arthritis. Of relevance, approximately 50% of patients with systemic sclerosis and RP experience digital ulcers, which can cause considerable pain and functional impairment.</div><div>The clinical cases described in this article correspond to a 33-year-old woman and an 18-year-old man with RP and digital ulcers. The woman showed no improvement despite medical treatment, while the man experienced healing of his lesions.</div><div>The pathophysiology of RF involves genetic and environmental factors, and the management of digital ulcers requires a multidisciplinary approach, combining medical care with wound care and the use of vasodilators. Although rare, digital ulcers represent a significant challenge that needs further research and better treatment options.</div><div>The aim of this paper is to describe the clinical features, laboratory, complementary studies, treatment and evolution of two patients with digital ulcers.</div></div>\",\"PeriodicalId\":31544,\"journal\":{\"name\":\"Revista Medica Clinica Las Condes\",\"volume\":\"36 2\",\"pages\":\"Pages 88-92\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Medica Clinica Las Condes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0716864025000252\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Medica Clinica Las Condes","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0716864025000252","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Cuando el fenómeno de Raynaud se acompaña de las temidas úlceras digitales: reporte de dos casos
Raynaud's phenomenon (RP) is a vasospastic disorder, often triggered by cold or stress, that causes changes in the color of the fingers due to excessive vasoconstriction. A prevalence ranging from 5% to 14.5% has been described. Between 5% and 10% of patients with RP develop autoimmune diseases, such as systemic sclerosis, systemic lupus erythematosus, or rheumatoid arthritis. Of relevance, approximately 50% of patients with systemic sclerosis and RP experience digital ulcers, which can cause considerable pain and functional impairment.
The clinical cases described in this article correspond to a 33-year-old woman and an 18-year-old man with RP and digital ulcers. The woman showed no improvement despite medical treatment, while the man experienced healing of his lesions.
The pathophysiology of RF involves genetic and environmental factors, and the management of digital ulcers requires a multidisciplinary approach, combining medical care with wound care and the use of vasodilators. Although rare, digital ulcers represent a significant challenge that needs further research and better treatment options.
The aim of this paper is to describe the clinical features, laboratory, complementary studies, treatment and evolution of two patients with digital ulcers.