病例报告：喹硫平引起的肌阵挛

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL

Revista Medica Clinica Las Condes Pub Date : 2025-03-01 DOI:10.1016/j.rmclc.2025.03.005

Marcos Franchello MD , Ximena Sagues MD , Jerónimo Cossio MD , Griselda Alvarado MD

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引用次数: 0

摘要

喹硫平是一种非典型抗精神病药，衍生自二苯并噻唑类药物，因其安全性提高而被广泛使用，特别是在帕金森病患者中。尽管其良好的形象，有孤立的报告，由这种药物引起的肌阵挛，即使在低剂量。我们提出了一例71岁的帕金森病患者，在给予亚治疗水平的喹硫平（12.5毫克）后，出现了肌颤。停药后肌阵挛完全消失，并引入氯硝西泮，突出认识到这种罕见的不良反应的重要性。

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Reporte de caso: mioclonias inducidas por quetiapina

Quetiapine is an atypical antipsychotic, derived from dibenzothiazepine, widely used for its improved safety profile, particularly in patients with Parkinson's disease. Despite its favorable profile, there have been isolated reports of myoclonus induced by this drug, even at low doses. We present the case of a 71-year-old patient with Parkinson's disease who developed myoclonus after administration of quetiapine at subtherapeutic levels (12.5 mg). The myoclonus completely resolved after discontinuation of the drug and the introduction of clonazepam, highlighting the importance of recognizing this rare adverse effect.

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来源期刊

Revista Medica Clinica Las Condes MEDICINE, GENERAL & INTERNAL-

CiteScore

0.80

自引率

0.00%

发文量

审稿时长

81 days