基于正颌治疗预测的面部手术预览

IF 4.9 2区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Huijun Han , Congyi Zhang , Lifeng Zhu , Pradeep Singh , Richard Tai-Chiu Hsung , Yiu Yan Leung , Taku Komura , Wenping Wang , Min Gu
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引用次数: 0

摘要

背景和目的:正颌外科会诊对于帮助患者了解手术后面部外观可能发生的变化至关重要。然而,由于治疗前后数据有限以及治疗的复杂性,目前的可视化方法往往效率低下且不准确。本研究旨在开发一种完全自动化的管道,用于在不需要额外医学图像的情况下生成准确高效的术后面部外观3D预览。方法:提出的方法结合口腔凹凸性和不对称性等新的美学标准来提高预测精度。为了解决数据限制,实现了一个健壮的数据增强方案。性能是根据最先进的方法评估使用倒角距离和豪斯多夫距离指标。此外,还进行了一项涉及医疗专业人员和工程师的用户研究,以评估预测模型的有效性。参与者将机器学习生成的人脸与实际手术结果进行盲法比较,并使用McNemar的测试来分析其分化的稳健性。结果:定量评价表明,该方法预测精度高,豪斯多夫距离为9.00 mm,倒角距离为2.50 mm,优于目前的预测水平。即使没有额外的合成数据,我们的方法也获得了有竞争力的结果(Hausdorff Distance: 9.43 mm, Chamfer Distance: 2.94 mm)。定性结果显示准确的面部预测。分析显示,与医学专业人员相比,工程师的灵敏度(54.20%比53.30%)和精度(50.20%比49.40%)略高,尽管两组的特异性都较低,约为46%。统计检验显示,机器学习生成的人脸与真实手术结果的区分差异无统计学意义,p值分别为0.567和0.256。消融测试证明了我们的损失函数和数据增强在提高预测精度方面的贡献。结论:本研究为正颌外科会诊提供了一种实用有效的解决方案,提高了术后3D面部外观预览的效率和准确性,使医患双方受益。该方法在术前可视化和辅助决策方面具有潜在的实际应用价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Facial surgery preview based on the orthognathic treatment prediction

Facial surgery preview based on the orthognathic treatment prediction

Background and Objective:

Orthognathic surgery consultations are essential for helping patients understand how their facial appearance may change after surgery. However, current visualization methods are often inefficient and inaccurate due to limited pre- and post-treatment data and the complexity of the treatment. This study aims to develop a fully automated pipeline for generating accurate and efficient 3D previews of postsurgical facial appearances without requiring additional medical images.

Methods:

The proposed method incorporates novel aesthetic criteria, such as mouth-convexity and asymmetry, to improve prediction accuracy. To address data limitations, a robust data augmentation scheme is implemented. Performance is evaluated against state-of-the-art methods using Chamfer distance and Hausdorff distance metrics. Additionally, a user study involving medical professionals and engineers was conducted to evaluate the effectiveness of the predicted models. Participants performed blinded comparisons of machine learning-generated faces and real surgical outcomes, with McNemar’s test used to analyze the robustness of their differentiation.

Results:

Quantitative evaluations showed high prediction accuracy for our method, with a Hausdorff Distance of 9.00 millimeters and Chamfer Distance of 2.50 millimeters, outperforming the state of the art. Even without additional synthesized data, our method achieved competitive results (Hausdorff Distance: 9.43 millimeters, Chamfer Distance: 2.94 millimeters). Qualitative results demonstrated accurate facial predictions. The analysis revealed slightly higher sensitivity (54.20% compared to 53.30%) and precision (50.20% compared to 49.40%) for engineers compared to medical professionals, though both groups had low specificity, approximately 46%. Statistical tests showed no significant difference in distinguishing Machine Learning-Generated faces from Real Surgical Outcomes, with p-values of 0.567 and 0.256, respectively. Ablation tests demonstrated the contribution of our loss functions and data augmentation in enhancing prediction accuracy.

Conclusion:

This study provides a practical and effective solution for orthognathic surgery consultations, benefiting both doctors and patients by improving the efficiency and accuracy of 3D postsurgical facial appearance previews. The proposed method has the potential for practical application in pre-surgical visualization and aiding in decision-making.
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来源期刊
Computer methods and programs in biomedicine
Computer methods and programs in biomedicine 工程技术-工程:生物医学
CiteScore
12.30
自引率
6.60%
发文量
601
审稿时长
135 days
期刊介绍: To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine. Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.
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