{"title":"穿孔切除联合浅表x线治疗瘢痕疙瘩的疗效：单中心回顾性研究","authors":"Junyou Zheng, Fang Fang, Wenbo Bu","doi":"10.1155/dth/4327219","DOIUrl":null,"url":null,"abstract":"<div>\n <p><b>Background:</b> Keloid management remains a challenge for clinicians. Recently, punch excision and photoelectric technology have demonstrated promising clinical applications for managing keloids; however, few studies have examined the efficacy and safety of punch excision combined with superficial X-ray for treating keloids.</p>\n <p><b>Objective:</b> To investigate the efficacy and safety of punch excision combined with superficial X-ray for treating keloid.</p>\n <p><b>Methods:</b> In this retrospective study, we analyzed the clinical records of 60 patients with keloid scars who underwent punch excision combined with superficial X-ray at our hospital, from April 2020 to April 2023. The Vancouver Scar Scale (VSS) and Patient and Observer Scar Assessment Scale (POSAS) 2.0 Patient Scale serve as the primary assessment tools to evaluate all patients, both prior to the initial treatment and one year after the completion of therapy. SPSS software was used for statistical analysis to assess keloid improvement.</p>\n <p><b>Results:</b> In the 60 patients with keloids, varying degrees of improvement were observed. The VSS and POSAS scores recorded 1 year after treatment were significantly lower than the pretreatment scores (<i>p</i> < 0.001). No severe adverse reactions were observed during treatment.</p>\n <p><b>Conclusion:</b> The combination of punch excision and superficial X-ray demonstrated a notable therapeutic effect on keloids without evident adverse reactions, offering a safe and effective option for patients with keloids.</p>\n <p><b>Trial Registration:</b> Chinese Registry of Clinical Trials: ChiCTR2400094289</p>\n </div>","PeriodicalId":11045,"journal":{"name":"Dermatologic Therapy","volume":"2025 1","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/dth/4327219","citationCount":"0","resultStr":"{\"title\":\"Efficacy of Punch Excision Combined With Superficial X-Ray for the Treatment of Keloids: A Single-Center Retrospective Study\",\"authors\":\"Junyou Zheng, Fang Fang, Wenbo Bu\",\"doi\":\"10.1155/dth/4327219\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n <p><b>Background:</b> Keloid management remains a challenge for clinicians. Recently, punch excision and photoelectric technology have demonstrated promising clinical applications for managing keloids; however, few studies have examined the efficacy and safety of punch excision combined with superficial X-ray for treating keloids.</p>\\n <p><b>Objective:</b> To investigate the efficacy and safety of punch excision combined with superficial X-ray for treating keloid.</p>\\n <p><b>Methods:</b> In this retrospective study, we analyzed the clinical records of 60 patients with keloid scars who underwent punch excision combined with superficial X-ray at our hospital, from April 2020 to April 2023. The Vancouver Scar Scale (VSS) and Patient and Observer Scar Assessment Scale (POSAS) 2.0 Patient Scale serve as the primary assessment tools to evaluate all patients, both prior to the initial treatment and one year after the completion of therapy. SPSS software was used for statistical analysis to assess keloid improvement.</p>\\n <p><b>Results:</b> In the 60 patients with keloids, varying degrees of improvement were observed. The VSS and POSAS scores recorded 1 year after treatment were significantly lower than the pretreatment scores (<i>p</i> < 0.001). No severe adverse reactions were observed during treatment.</p>\\n <p><b>Conclusion:</b> The combination of punch excision and superficial X-ray demonstrated a notable therapeutic effect on keloids without evident adverse reactions, offering a safe and effective option for patients with keloids.</p>\\n <p><b>Trial Registration:</b> Chinese Registry of Clinical Trials: ChiCTR2400094289</p>\\n </div>\",\"PeriodicalId\":11045,\"journal\":{\"name\":\"Dermatologic Therapy\",\"volume\":\"2025 1\",\"pages\":\"\"},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2025-04-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1155/dth/4327219\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dermatologic Therapy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1155/dth/4327219\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dermatologic Therapy","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1155/dth/4327219","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Efficacy of Punch Excision Combined With Superficial X-Ray for the Treatment of Keloids: A Single-Center Retrospective Study
Background: Keloid management remains a challenge for clinicians. Recently, punch excision and photoelectric technology have demonstrated promising clinical applications for managing keloids; however, few studies have examined the efficacy and safety of punch excision combined with superficial X-ray for treating keloids.
Objective: To investigate the efficacy and safety of punch excision combined with superficial X-ray for treating keloid.
Methods: In this retrospective study, we analyzed the clinical records of 60 patients with keloid scars who underwent punch excision combined with superficial X-ray at our hospital, from April 2020 to April 2023. The Vancouver Scar Scale (VSS) and Patient and Observer Scar Assessment Scale (POSAS) 2.0 Patient Scale serve as the primary assessment tools to evaluate all patients, both prior to the initial treatment and one year after the completion of therapy. SPSS software was used for statistical analysis to assess keloid improvement.
Results: In the 60 patients with keloids, varying degrees of improvement were observed. The VSS and POSAS scores recorded 1 year after treatment were significantly lower than the pretreatment scores (p < 0.001). No severe adverse reactions were observed during treatment.
Conclusion: The combination of punch excision and superficial X-ray demonstrated a notable therapeutic effect on keloids without evident adverse reactions, offering a safe and effective option for patients with keloids.
Trial Registration: Chinese Registry of Clinical Trials: ChiCTR2400094289
期刊介绍：
Dermatologic Therapy has been created to fill an important void in the dermatologic literature: the lack of a readily available source of up-to-date information on the treatment of specific cutaneous diseases and the practical application of specific treatment modalities. Each issue of the journal consists of a series of scholarly review articles written by leaders in dermatology in which they describe, in very specific terms, how they treat particular cutaneous diseases and how they use specific therapeutic agents. The information contained in each issue is so practical and detailed that the reader should be able to directly apply various treatment approaches to daily clinical situations. Because of the specific and practical nature of this publication, Dermatologic Therapy not only serves as a readily available resource for the day-to-day treatment of patients, but also as an evolving therapeutic textbook for the treatment of dermatologic diseases.
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