磁共振成像和直线加速器联合系统对乳糜泻轴描绘和治疗的可行性

IF 3.4 Q2 ONCOLOGY

Physics and Imaging in Radiation Oncology Pub Date : 2025-04-01 DOI:10.1016/j.phro.2025.100768

Sara N. Lim , Yirong Liu , Anugayathri Jawahar , Bharat B. Mittal , Tarita O. Thomas

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引用次数: 0

摘要

已经进行了对腹腔神经丛照射治疗胰腺癌疼痛的试验。对10例患者的联合磁共振成像和线性加速器系统（MR-linac）图像进行评估，以描绘腹腔神经节，旨在缩小靶体积，降低治疗风险，而不是标准的基于线性加速器的治疗。mri线性线显示出优越的软组织对比，与常规线性线相比，可以在照射较小靶体积的同时增加对神经节的剂量(中位数：0.8 cm3 vs. 32.2 cm3, p <；10对方案0.05)。虽然需要进一步的研究，但MR-linac治疗可以提高靶向精度，减少对危险器官的剂量，提高姑息治疗的有效性。

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Feasibility of celiac axis delineation and treatment on combined magnetic resonance imaging and linear accelerator systems

Trials have been performed on irradiating celiac plexus for pancreatic cancer pain management. Images from a combined magnetic resonance imaging and linear accelerator system (MR-linac) for ten patients were assessed for delineation of celiac ganglia, aiming for smaller target volumes and reducing treatment risks versus standard linac-based treatments. MRI-linacs showed superior soft tissue contrast, enabling increased dose to ganglia while irradiating smaller target volumes versus regular linacs (median: 0.8 cm³ vs. 32.2 cm³, p < 0.05 for ten pairs of plans). While further studies are needed, MR-linac treatments could improve targeting precision, minimize dose to organs-at-risk and enhance effectiveness in palliative care.

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来源期刊

Physics and Imaging in Radiation Oncology Physics and Astronomy-Radiation

CiteScore

5.30

自引率

18.90%

发文量

审稿时长

6 weeks