针对乳腺下窝内侧支的腰椎小关节去神经支配:一项解剖学优化研究

John Tran , Aaron Conger , Keaton Lightfoot , Zachary L. McCormick , Eldon Loh
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摘要

最近的解剖学研究发现,在腰椎小关节脱神经时,乳突下窝是延长长度和更可靠地捕获内侧支的潜在靶点。尽管发表了一系列临床病例,描述了针对乳腺下窝的积极结果,但射频插管放置的理想位置尚未得到评估。进一步的解剖研究这种新技术是必要的,以完善透视标志的最佳位置。方法12根套管在透视引导下放置,瞄准L3, L4, &;2具尸体标本中L5内侧分支。采用解剖、数字化和高保真三维建模方法来识别透视标记。在三维模型上进行病变模拟以分析神经捕获。结果在12个放置点中,有5个(41.7%)的内侧支捕获率被归类为“完全”,即模拟病变与内侧支主干或其所有远端分支重叠。在12个位置中的4个(33.3%)中,神经捕获率是“部分”的,至少有一个远端分支超出了模拟病变的边界。在其余3个位置(25.0%)中,捕获率被归类为“无”,因为内侧分支主干和所有远端分支都超越了模拟病变边界。提出的精细透视标志为乳腺突外侧边界(AP视图);小关节线乳突-副切迹/下边界(斜视图);以及乳腺突的下侧面(侧面)。结论:本解剖优化研究采用解剖、成像相关性和高保真模型来评估在腰椎小关节去神经控制中,在乳突下窝捕获内侧支的插管位置。基于目前的分析,提出了改进的透视标志,以供进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lumbar facet joint denervation targeting the medial branch in the sub-mammillary fossa: An anatomical optimization study

Introduction

Recent anatomical studies have identified the sub-mammillary fossa as a potential target site to extend the length and more reliably capture the medial branch during lumbar facet joint denervation. Although a clinical case series was published describing positive outcomes targeting the sub-mammillary fossa, the ideal location for radiofrequency cannula placement has not been assessed. Further anatomical investigation of this novel technique is warranted to refine fluoroscopic landmarks for optimal placement.

Methods

Twelve cannulae were placed under fluoroscopic guidance targeting the L3, L4, & L5 medial branches in 2 embalmed cadaveric specimens. Dissection, digitization, and high-fidelity 3D modelling methodology was used to identify fluoroscopic landmarks. Lesion simulation was performed on 3D models to analyze nerve capture.

Results

In 5 of 12 placements (41.7 %), the medial branch capture rate was classified as “complete,” as the simulated lesion overlapped with the medial branch trunk or all of its distal branches. In 4 of 12 placements (33.3 %), the nerve capture rate was “partial” with at least one distal branch found beyond the boundary of the simulated lesion. In the remaining 3 placements (25.0 %), the capture rate was classified as “none,” as the medial branch trunk and all distal branches transited beyond the simulated lesion boundary. Refined fluoroscopic landmarks proposed were the lateral boundary of mammillary process (AP view); the mamillo-accessory notch/inferior boundary of facet joint line (oblique view); and the inferior aspect of the mammillary process (lateral view).

Conclusions

This anatomy optimization study used dissection, imaging correlation, and high-fidelity modelling to assess cannula placement for capture of the medial branch at the sub-mammillary fossa for lumbar facet joint denervation. Based on the present analysis, refined fluoroscopic landmarks were proposed for further investigation.
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