{"title":"加纳结直肠癌分析:对中低收入国家的启示","authors":"Olajumoke M. Megafu","doi":"10.1016/j.amjsurg.2025.116350","DOIUrl":null,"url":null,"abstract":"<div><div>Colorectal cancer (CRC) is a growing public health threat in low- and middle-income countries (LMICs), challenging the traditional focus on infectious diseases. This paper examines the rising burden of CRC in LMICs, using Ghana as a case study. CRC incidence is increasing in LMICs, often presenting at younger ages and later stages, with poorer survival rates. This analysis explores CRC's epidemiological trends in Ghana, highlighting management challenges: limited resources, inadequate screening, sociocultural barriers, and social determinants of health. The paper investigates the roles of stakeholders, government agencies, and frontline providers in shaping healthcare infrastructure and addressing the need for specialized care. It examines the gap in global health initiatives regarding chronic diseases such as CRC and funding/policy prioritization challenges. Finally, it proposes policy recommendations for LMICs: robust surveillance systems, tailored screening guidelines, integrated preventive measures, improved access to screening and treatment, and collaborative efforts. Addressing CRC's complex challenges in LMICs requires a shift in global health priorities, recognizing the increasing burden of chronic diseases and ensuring equitable access to prevention, screening, and treatment.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"245 ","pages":"Article 116350"},"PeriodicalIF":2.7000,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An analysis of colorectal cancer in Ghana: implications for low and middle income countries\",\"authors\":\"Olajumoke M. Megafu\",\"doi\":\"10.1016/j.amjsurg.2025.116350\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Colorectal cancer (CRC) is a growing public health threat in low- and middle-income countries (LMICs), challenging the traditional focus on infectious diseases. This paper examines the rising burden of CRC in LMICs, using Ghana as a case study. CRC incidence is increasing in LMICs, often presenting at younger ages and later stages, with poorer survival rates. This analysis explores CRC's epidemiological trends in Ghana, highlighting management challenges: limited resources, inadequate screening, sociocultural barriers, and social determinants of health. The paper investigates the roles of stakeholders, government agencies, and frontline providers in shaping healthcare infrastructure and addressing the need for specialized care. It examines the gap in global health initiatives regarding chronic diseases such as CRC and funding/policy prioritization challenges. Finally, it proposes policy recommendations for LMICs: robust surveillance systems, tailored screening guidelines, integrated preventive measures, improved access to screening and treatment, and collaborative efforts. Addressing CRC's complex challenges in LMICs requires a shift in global health priorities, recognizing the increasing burden of chronic diseases and ensuring equitable access to prevention, screening, and treatment.</div></div>\",\"PeriodicalId\":7771,\"journal\":{\"name\":\"American journal of surgery\",\"volume\":\"245 \",\"pages\":\"Article 116350\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-04-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0002961025001722\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of surgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0002961025001722","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"SURGERY","Score":null,"Total":0}
An analysis of colorectal cancer in Ghana: implications for low and middle income countries
Colorectal cancer (CRC) is a growing public health threat in low- and middle-income countries (LMICs), challenging the traditional focus on infectious diseases. This paper examines the rising burden of CRC in LMICs, using Ghana as a case study. CRC incidence is increasing in LMICs, often presenting at younger ages and later stages, with poorer survival rates. This analysis explores CRC's epidemiological trends in Ghana, highlighting management challenges: limited resources, inadequate screening, sociocultural barriers, and social determinants of health. The paper investigates the roles of stakeholders, government agencies, and frontline providers in shaping healthcare infrastructure and addressing the need for specialized care. It examines the gap in global health initiatives regarding chronic diseases such as CRC and funding/policy prioritization challenges. Finally, it proposes policy recommendations for LMICs: robust surveillance systems, tailored screening guidelines, integrated preventive measures, improved access to screening and treatment, and collaborative efforts. Addressing CRC's complex challenges in LMICs requires a shift in global health priorities, recognizing the increasing burden of chronic diseases and ensuring equitable access to prevention, screening, and treatment.
期刊介绍:
The American Journal of Surgery® is a peer-reviewed journal designed for the general surgeon who performs abdominal, cancer, vascular, head and neck, breast, colorectal, and other forms of surgery. AJS is the official journal of 7 major surgical societies* and publishes their official papers as well as independently submitted clinical studies, editorials, reviews, brief reports, correspondence and book reviews.