铂催化缩醛与烯基硅烷的烯基化反应

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-04-03 DOI:10.1021/acs.orglett.5c0109610.1021/acs.orglett.5c01096

Toma Hattori, Juri Matsuda-Komuro, Yuji Sakurazawa, Naoto Chijiwa, Daiki Fukuda, Hidenori Kinoshita and Katsukiyo Miura*,

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引用次数: 0

摘要

在催化剂 PtCl2 和 LiI 的作用下，烯基硅烷与乙腈中芳香醛的二甲基乙醛发生反应，生成烯丙基甲基醚。这种烯化反应不是发生在与硅结合的 α 碳上，而是发生在烯基硅烷的 β 碳上。使用三甲基氯硅烷作为添加剂可有效促进某些乙醛的烯化反应。在 PtCl2 催化下，末端炔烃与三乙基硅烷发生氢硅烷化反应，随后炔烃发生烯丙基化反应，从而轻松快速地合成了烯丙基醚。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Platinum-Catalyzed Alkenylation of Acetals with Alkenylsilanes

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Platinum-Catalyzed Alkenylation of Acetals with Alkenylsilanes

In the presence of catalytic amounts of PtCl₂ and LiI, alkenylsilanes reacted with dimethyl acetals of aromatic aldehydes in acetonitrile to give allylic methyl ethers. This alkenylation reaction occurred not at the α-carbon bound to silicon but at the β-carbon of alkenylsilanes. Use of chlorotrimethylsilane as an additive was effective in promoting the alkenylation of certain acetals. The PtCl₂-catalyzed hydrosilylation of terminal alkynes with triethylsilane and subsequent alkenylation of acetals enabled easy and rapid synthesis of allylic ethers.

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.