追踪RNA诞生时的折叠过程

IF 14.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Cell Pub Date : 2025-04-17 DOI:10.1016/j.molcel.2025.03.022

Jinsong Zhang, Qiangfeng Cliff Zhang

引用次数: 0

摘要

在本期的Molecular Cell中，Schärfen等人1描述了一种称为CoSTseq的先进RNA结构探测技术，该技术可以在活酵母细胞转录过程中对新生RNA碱基配对进行转录组范围的检测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Tracking the folding of RNA at its birth

In this issue of Molecular Cell, Schärfen et al.¹ describe an advanced RNA structure-probing technology called CoSTseq that enables transcriptome-wide detection of nascent RNA base pairing during transcription in living yeast cells.

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来源期刊

Molecular Cell 生物-生化与分子生物学

CiteScore

26.00

自引率

3.80%

发文量

389

审稿时长

1 months

期刊介绍： Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.