《触屏测试研究认知的神经化学》特刊前言

IF 4.2 3区 医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Miguel Skirzewski, Lisa M. Saksida, Tim J. Bussey
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引用次数: 0

摘要

基于触摸屏的方法通过在啮齿动物模型中提供标准化的、翻译相关的高级认知功能评估,使认知神经科学取得了重大进展。本期特刊强调了这些系统在动物和人类研究方面的潜力,提供了对认知基础的神经化学和生物学机制的见解。纳入的研究探索了多种应用,从了解慢性应激和母体免疫激活的认知影响到评估新疗法的有效性,以及评估提高翻译相关性的跨物种认知测试方法。通过将触摸屏技术与电生理学和开放科学数据库等前沿方法相结合,这些贡献强调了自动化系统在推进转化研究中的关键作用。他们共同为解决脑部疾病认知缺陷的新治疗策略奠定了基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Preface to the Special Issue “Touchscreen Testing to Investigate the Neurochemistry of Cognition”

Preface to the Special Issue “Touchscreen Testing to Investigate the Neurochemistry of Cognition”

Touchscreen-based methodologies have enabled significant advancements in cognitive neuroscience by providing standardized, translationally relevant assessments of advanced cognitive functions in rodent models. This special issue highlights the potential of these systems to bridge animal and human research, providing insights into the neurochemical and biological mechanisms underlying cognition. The included studies explore diverse applications, from understanding the cognitive impacts of chronic stress and maternal immune activation to evaluating the effectiveness of novel therapeutics and assessing cross-species cognitive testing approaches that enhance translational relevance. By combining touchscreen technologies with cutting-edge approaches like electrophysiology and open science databases, these contributions underscore the critical role of automated systems in advancing translational research. Together, they lay the foundation for novel therapeutic strategies to address cognitive deficits in brain disorders.

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来源期刊
Journal of Neurochemistry
Journal of Neurochemistry 医学-神经科学
CiteScore
9.30
自引率
2.10%
发文量
181
审稿时长
2.2 months
期刊介绍: Journal of Neurochemistry focuses on molecular, cellular and biochemical aspects of the nervous system, the pathogenesis of neurological disorders and the development of disease specific biomarkers. It is devoted to the prompt publication of original findings of the highest scientific priority and value that provide novel mechanistic insights, represent a clear advance over previous studies and have the potential to generate exciting future research.
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