Akshay Chauhan MBBS , Nischal Ranganath MD, PhD , John P. Scott MD , Paschalis Vergidis MD , Anja C. Roden MD , Philip J. Spencer MD , Mauricio A. Villavicencio MD , Richard C. Daly MD , Sahar A. Saddoughi MD, PhD
{"title":"曾接受过心肺移植手术的患者因患侵袭性肺孢子虫病而重新接受双侧肺移植手术","authors":"Akshay Chauhan MBBS , Nischal Ranganath MD, PhD , John P. Scott MD , Paschalis Vergidis MD , Anja C. Roden MD , Philip J. Spencer MD , Mauricio A. Villavicencio MD , Richard C. Daly MD , Sahar A. Saddoughi MD, PhD","doi":"10.1016/j.jhlto.2025.100247","DOIUrl":null,"url":null,"abstract":"<div><div>Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive <em>Scedosporium</em> apiospermum infection. The patient underwent a redo-bilateral lung transplant followed by a combination of inhaled voriconazole, caspofungin, and olorofim for a prolonged period. We observed no issues with bronchial anastomosis healing, and the patient is doing well on 1-year follow-up. This report outlines a successful management approach to this rare complication of heart-lung transplant recipients.</div></div>","PeriodicalId":100741,"journal":{"name":"JHLT Open","volume":"8 ","pages":"Article 100247"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis\",\"authors\":\"Akshay Chauhan MBBS , Nischal Ranganath MD, PhD , John P. Scott MD , Paschalis Vergidis MD , Anja C. Roden MD , Philip J. Spencer MD , Mauricio A. Villavicencio MD , Richard C. Daly MD , Sahar A. Saddoughi MD, PhD\",\"doi\":\"10.1016/j.jhlto.2025.100247\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive <em>Scedosporium</em> apiospermum infection. The patient underwent a redo-bilateral lung transplant followed by a combination of inhaled voriconazole, caspofungin, and olorofim for a prolonged period. We observed no issues with bronchial anastomosis healing, and the patient is doing well on 1-year follow-up. This report outlines a successful management approach to this rare complication of heart-lung transplant recipients.</div></div>\",\"PeriodicalId\":100741,\"journal\":{\"name\":\"JHLT Open\",\"volume\":\"8 \",\"pages\":\"Article 100247\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JHLT Open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2950133425000424\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JHLT Open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2950133425000424","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Redo bilateral lung transplantation in a previous heart-lung transplant recipient for invasive pulmonary scedosporiosis
Redo-bilateral lung transplant in previous heart-lung transplant is a rare operation. We describe our surgical and medical management experience with a heart-lung transplant recipient who developed chronic lung allograft dysfunction and invasive Scedosporium apiospermum infection. The patient underwent a redo-bilateral lung transplant followed by a combination of inhaled voriconazole, caspofungin, and olorofim for a prolonged period. We observed no issues with bronchial anastomosis healing, and the patient is doing well on 1-year follow-up. This report outlines a successful management approach to this rare complication of heart-lung transplant recipients.