用旋转磁场和金属棒研究芳氯与烷基氯的亲电偶联

IF 15.6 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Journal of the American Chemical Society Pub Date : 2025-04-01 DOI:10.1021/jacs.5c0038110.1021/jacs.5c00381

Xiaomei Feng, Xiangye Li, Ning Zhang, Lizhi Zhang, Fenggang Sun, Hui Liu, Zengdian Zhao and Xinjin Li*,

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引用次数: 0

摘要

追求可持续和环保的方法和技术继续挑战有机化学家。在此，我们报告了一种新方法的发展，其中电磁感应可以参与使用旋转磁场和金属棒的有机氯化物的耦合。特别地，我们描述了这一策略在镍催化芳氯与烷基氯的交叉亲电偶联中的应用。使用这些丰富的和商业上可获得的有机氯化物，这样的系统允许在温和条件下比目前的方案更广泛的范围进行反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Cross-Electrophile Coupling of Aryl Chlorides with Alkyl Chlorides Using Rotating Magnetic Field and Metal Rods

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Cross-Electrophile Coupling of Aryl Chlorides with Alkyl Chlorides Using Rotating Magnetic Field and Metal Rods

The pursuit of sustainable and environmentally benign methods and techniques continues to challenge organic chemists. Herein, we report the development of a novel approach in which electromagnetic induction could participate in the coupling of organic chlorides using a rotating magnetic field and metal rods. In particular, we describe the application of this strategy to the nickel-catalyzed cross-electrophile coupling of aryl chlorides with alkyl chlorides. Using these abundant and commercially available organochlorides, such a system allows reactions to proceed with a broader scope than the current protocols under mild conditions.

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来源期刊

Journal of the American Chemical Society 化学-化学综合

CiteScore

24.40

自引率

6.00%

发文量

2398

审稿时长

1.6 months

期刊介绍： The flagship journal of the American Chemical Society, known as the Journal of the American Chemical Society (JACS), has been a prestigious publication since its establishment in 1879. It holds a preeminent position in the field of chemistry and related interdisciplinary sciences. JACS is committed to disseminating cutting-edge research papers, covering a wide range of topics, and encompasses approximately 19,000 pages of Articles, Communications, and Perspectives annually. With a weekly publication frequency, JACS plays a vital role in advancing the field of chemistry by providing essential research.