{"title":"美国农业部有条件批准 H5N1 家禽疫苗","authors":"","doi":"10.1038/s41587-025-02658-0","DOIUrl":null,"url":null,"abstract":"<p>The US Department of Agriculture (USDA) has given a conditional approval to animal healthcare company Zoetis for an updated vaccine to protect poultry against the H5N1 bird flu strain. The Zoetis vaccine contains a killed version of an H5N2 variant that the company designed to work against currently circulating variants of the H5N1 virus.</p><p>The avian influenza has been spreading in dairy cow and poultry farms in the United States, causing at least several dozen infections in humans and one death. Although vaccination can help control the virus spread, the US government has long resisted its use, unlike those of China, Mexico, Egypt and France, where poultry are vaccinated against avian flu. So far, highly pathogenic influenza viruses have been eliminated from affected flocks by euthanasia. But this strategy has failed to eradicate the H5N1 viruses of the clade 2.3.4.4b that has been circulating in the country since February 2022.</p>","PeriodicalId":19084,"journal":{"name":"Nature biotechnology","volume":"60 1","pages":""},"PeriodicalIF":33.1000,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"USDA conditionally approves H5N1 poultry vaccine\",\"authors\":\"\",\"doi\":\"10.1038/s41587-025-02658-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The US Department of Agriculture (USDA) has given a conditional approval to animal healthcare company Zoetis for an updated vaccine to protect poultry against the H5N1 bird flu strain. The Zoetis vaccine contains a killed version of an H5N2 variant that the company designed to work against currently circulating variants of the H5N1 virus.</p><p>The avian influenza has been spreading in dairy cow and poultry farms in the United States, causing at least several dozen infections in humans and one death. Although vaccination can help control the virus spread, the US government has long resisted its use, unlike those of China, Mexico, Egypt and France, where poultry are vaccinated against avian flu. So far, highly pathogenic influenza viruses have been eliminated from affected flocks by euthanasia. But this strategy has failed to eradicate the H5N1 viruses of the clade 2.3.4.4b that has been circulating in the country since February 2022.</p>\",\"PeriodicalId\":19084,\"journal\":{\"name\":\"Nature biotechnology\",\"volume\":\"60 1\",\"pages\":\"\"},\"PeriodicalIF\":33.1000,\"publicationDate\":\"2025-04-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature biotechnology\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1038/s41587-025-02658-0\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature biotechnology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1038/s41587-025-02658-0","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
The US Department of Agriculture (USDA) has given a conditional approval to animal healthcare company Zoetis for an updated vaccine to protect poultry against the H5N1 bird flu strain. The Zoetis vaccine contains a killed version of an H5N2 variant that the company designed to work against currently circulating variants of the H5N1 virus.
The avian influenza has been spreading in dairy cow and poultry farms in the United States, causing at least several dozen infections in humans and one death. Although vaccination can help control the virus spread, the US government has long resisted its use, unlike those of China, Mexico, Egypt and France, where poultry are vaccinated against avian flu. So far, highly pathogenic influenza viruses have been eliminated from affected flocks by euthanasia. But this strategy has failed to eradicate the H5N1 viruses of the clade 2.3.4.4b that has been circulating in the country since February 2022.
期刊介绍：
Nature Biotechnology is a monthly journal that focuses on the science and business of biotechnology. It covers a wide range of topics including technology/methodology advancements in the biological, biomedical, agricultural, and environmental sciences. The journal also explores the commercial, political, ethical, legal, and societal aspects of this research.
The journal serves researchers by providing peer-reviewed research papers in the field of biotechnology. It also serves the business community by delivering news about research developments. This approach ensures that both the scientific and business communities are well-informed and able to stay up-to-date on the latest advancements and opportunities in the field.
Some key areas of interest in which the journal actively seeks research papers include molecular engineering of nucleic acids and proteins, molecular therapy, large-scale biology, computational biology, regenerative medicine, imaging technology, analytical biotechnology, applied immunology, food and agricultural biotechnology, and environmental biotechnology.
In summary, Nature Biotechnology is a comprehensive journal that covers both the scientific and business aspects of biotechnology. It strives to provide researchers with valuable research papers and news while also delivering important scientific advancements to the business community.
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