用于上消化道检查的新型电缆传输磁控胶囊内窥镜系统的可行性和安全性

Ke Meng, Yan Li, Bin Yan, Fei Pan, Jingshuang Yan, Guanzhou Zhou, Haixu Chen, Xiaomei Zhang
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引用次数: 0

摘要

背景评价一种新型缆索传输磁控胶囊内镜(CT-MCE)系统用于上消化道检查的可行性和安全性。方法招募26名自愿接受上消化道内镜检查的患者(19名健康志愿者和7名有胃肠道症状的患者)。每个参与者在24小时内进行CT-MCE检查,然后进行常规胃镜检查。评估CT-MCE胶囊在上胃肠道的可操作性和可见性、不良事件和手术过程中的不适。以常规胃镜检查结果为标准,评价CT-MCE诊断上消化道病变的敏感性和特异性。结果食道各节段的可操作性均为“良好”。根据胃区可操作性良好的参与者比例如下:贲门(100.00%)、幽门(96.15%)、胃角(92.31%)、胃窦(88.46%)、胃底(84.62%)和胃体(73.08%)。在十二指肠球部和降十二指肠,分别只有20.83%和16.67%的参与者表现良好。所有参与者的食道、Z线和十二指肠球的可见性均被评为“优秀”或“良好”;96.15%和79.17%的受试者胃和十二指肠降部可见性良好。共检出41个病灶。CT-MCE诊断上消化道病变的敏感性为85.00%,特异性为98.15%。所有参与者均成功通过口腔取出CT-MCE胶囊。未发生严重不良事件或胶囊滞留。结论CT-MCE用于上消化道检查具有良好的可行性和安全性。该系统在检查食道和胃方面是有效的,没有胶囊潴留的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Feasibility and Safety of a Novel Cable-Transmitted Magnetically Controlled Capsule Endoscopy System for Upper Gastrointestinal Examination

Feasibility and Safety of a Novel Cable-Transmitted Magnetically Controlled Capsule Endoscopy System for Upper Gastrointestinal Examination

Background

To evaluate the feasibility and safety of a novel cable-transmitted magnetically controlled capsule endoscopy (CT-MCE) system for upper gastrointestinal examination.

Methods

Twenty-six participants (19 healthy volunteers and seven patients with gastrointestinal symptoms) willing to undergo upper gastrointestinal endoscopy were recruited. Each participant underwent CT-MCE followed by conventional gastroscopy within 24 h. Maneuverability and visibility of the CT-MCE capsule in the upper gastrointestinal tract, adverse events, and discomfort during the procedure were evaluated. The sensitivity and specificity of CT-MCE for diagnosing upper gastrointestinal lesions were evaluated using conventional gastroscopy findings as the standard.

Results

Maneuverability was graded as “good” for all segments of the esophagus. The percentage of participants in which maneuverability was good according to gastric region was as follows: cardia (100.00%), pylorus (96.15%), angulus (92.31%), antrum (88.46%), fundus (84.62%), and body (73.08%). In the duodenal bulb and descending duodenum, it was good in only 20.83% and 16.67% of participants, respectively. Visibility was graded as “excellent” or “good” in the esophagus, Z line, and duodenal bulb in all participants; excellent/good visibility was achieved in the stomach and descending duodenum in 96.15% and 79.17% of participants, respectively. Forty-one lesions were detected overall. The sensitivity and specificity of CT-MCE in diagnosing upper gastrointestinal lesions were 85.00% and 98.15%, respectively. The CT-MCE capsule was successfully removed through the mouth in all participants. No serious adverse events or capsule retention occurred.

Conclusions

CT-MCE showed good feasibility and safety for upper gastrointestinal examination. The system was effective in examining the esophagus and stomach with no risk of capsule retention.

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