Lag-Net:通过卷积神经网络对锥束 CT 进行滞后校正

IF 4.9 2区 医学 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Chenlong Ren , Shengqi Kan , Wenhui Huang , Yan Xi , Xu Ji , Yang Chen
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引用次数: 0

摘要

背景和目的:由于非晶硅平板探测器中电荷陷阱的存在,滞后信号在连续捕获的投影中产生。这些信号导致投影图像中的重影和锥形束计算机断层扫描(CBCT)重建中的严重滞后伪影。传统的线性时不变(LTI)校正需要测量滞后校正因子(LCF),并可能留下残留的滞后伪影。这种不完整的修正部分归因于缺乏对暴露依赖性的考虑。方法:为了更准确地测量滞后信号并抑制滞后伪影,我们开发了一种新的硬件校正方法。这种方法需要对同一物体进行两次扫描,并在第二次扫描期间调整CT仪器的工作时间,以测量第一次扫描的滞后信号。虽然这种硬件校正显著减轻了滞后现象,但实现起来很复杂,对CT仪器的要求也很高。为了增强这一过程,我们引入了一种称为lag- net的深度学习方法来去除滞后信号,利用硬件校正的几乎无滞后的结果作为网络的训练目标。结果:对模拟和真实数据集的实验结果进行定性和定量分析表明,深度学习校正在抑制滞后伪影和增强图像质量方面明显优于传统的LTI校正。此外,深度学习方法在避免硬件校正方法相关的操作复杂性的同时,获得了与硬件校正方法相当的重建结果。结论:所提出的硬件校正方法尽管操作复杂,但与LTI算法相比,具有更好的伪影抑制性能,特别是在低曝光条件下。引入的Lag-Net利用硬件校正方法的结果作为训练目标,利用深度学习的端到端特性来规避与硬件校正相关的复杂操作缺陷。此外,在低曝光场景下,网络的校正效率优于LTI算法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Lag-Net: Lag correction for cone-beam CT via a convolutional neural network

Lag-Net: Lag correction for cone-beam CT via a convolutional neural network

Background and objective:

Due to the presence of charge traps in amorphous silicon flat-panel detectors, lag signals are generated in consecutively captured projections. These signals lead to ghosting in projection images and severe lag artifacts in cone-beam computed tomography (CBCT) reconstructions. Traditional Linear Time-Invariant (LTI) correction need to measure lag correction factors (LCF) and may leave residual lag artifacts. This incomplete correction is partly attributed to the lack of consideration for exposure dependency.

Methods:

To measure the lag signals more accurately and suppress lag artifacts, we develop a novel hardware correction method. This method requires two scans of the same object, with adjustments to the operating timing of the CT instrumentation during the second scan to measure the lag signal from the first. While this hardware correction significantly mitigates lag artifacts, it is complex to implement and imposes high demands on the CT instrumentation. To enhance the process, We introduce a deep learning method called Lag-Net to remove lag signal, utilizing the nearly lag-free results from hardware correction as training targets for the network.

Results:

Qualitative and quantitative analyses of experimental results on both simulated and real datasets demonstrate that deep learning correction significantly outperforms traditional LTI correction in terms of lag artifact suppression and image quality enhancement. Furthermore, the deep learning method achieves reconstruction results comparable to those obtained from hardware correction while avoiding the operational complexities associated with the hardware correction approach.

Conclusion:

The proposed hardware correction method, despite its operational complexity, demonstrates superior artifact suppression performance compared to the LTI algorithm, particularly under low-exposure conditions. The introduced Lag-Net, which utilizes the results of the hardware correction method as training targets, leverages the end-to-end nature of deep learning to circumvent the intricate operational drawbacks associated with hardware correction. Furthermore, the network’s correction efficacy surpasses that of the LTI algorithm in low-exposure scenarios.
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来源期刊
Computer methods and programs in biomedicine
Computer methods and programs in biomedicine 工程技术-工程:生物医学
CiteScore
12.30
自引率
6.60%
发文量
601
审稿时长
135 days
期刊介绍: To encourage the development of formal computing methods, and their application in biomedical research and medical practice, by illustration of fundamental principles in biomedical informatics research; to stimulate basic research into application software design; to report the state of research of biomedical information processing projects; to report new computer methodologies applied in biomedical areas; the eventual distribution of demonstrable software to avoid duplication of effort; to provide a forum for discussion and improvement of existing software; to optimize contact between national organizations and regional user groups by promoting an international exchange of information on formal methods, standards and software in biomedicine. Computer Methods and Programs in Biomedicine covers computing methodology and software systems derived from computing science for implementation in all aspects of biomedical research and medical practice. It is designed to serve: biochemists; biologists; geneticists; immunologists; neuroscientists; pharmacologists; toxicologists; clinicians; epidemiologists; psychiatrists; psychologists; cardiologists; chemists; (radio)physicists; computer scientists; programmers and systems analysts; biomedical, clinical, electrical and other engineers; teachers of medical informatics and users of educational software.
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