Editorial expression of concern: Yin Yang-1 suppresses invasion and metastasis of pancreatic ductal adenocarcinoma by downregulating MMP10 in a MUC4/ErbB2/p38/MEF2C-dependent mechanism

Correction: Mol Cancer 13, 130 (2014)

https://doi.org/10.1186/1476-4598-13-130

The Editor-in-Chief is issuing an editorial expression of concern to alert readers that after the publication of this article, it was brought to the attention of the publisher that there are a number of image integrity concerns. There appear to be high similarities between Fig. 1e GAPDH and Fig. 3b GAPDH, representing different conditions. Figure 3d Invasion-BXPC-YY1 appears to partially overlap with Fig. 3d Migration-BXPC-Scramble shRNA. Figure 5a Erk1/2-Vector and Fig. 5a p-Erk1/2-YY1 shRNA also appear to be highly similar. The authors were able to provide the original cell images for Fig. 3d, but were unable to provide the original images for any of the blots. Readers are urged to take caution when interpreting the content and conclusions of this article.

Authors Jing-Jing Zhang. Yun-Peng Peng, Yi Miao, Kun-Ling Xie, and Yi Zhu agree with this Editorial Expression of Concern. All other authors have not responded to correspondence from the publisher regarding this Editorial Expression of Concern.

1. Zhang JJ, Zhu Y, Xie KL, et al. Yin Yang-1 suppresses invasion and metastasis of pancreatic ductal adenocarcinoma by downregulating MMP10 in a MUC4/ErbB2/p38/MEF2C-dependent mechanism. Mol Cancer. 2014;13:130. https://doi.org/10.1186/1476-4598-13-130.

   Article PubMed PubMed Central CAS Google Scholar

Download references

Authors and Affiliations

1. Department of General Surgery, Jiangsu Province Academy of Clinical Medicine, Institute of Tumor Biology, The first Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, People’s Republic of China

   Jing-Jing Zhang, Yi Zhu, Ze-Kuan Xu, Cun-Cai Dai, Zhu-Yin Qian, Kui-Rong Jiang, Jun-Li Wu, Wen-Tao Gao, Qing Du & Yi Miao

2. Jiangsu Province Academy of Clinical Medicine, Institute of Tumor Biology, 300 Guangzhou Road, Nanjing, 210029, People’s Republic of China

   Jing-Jing Zhang, Yi Zhu, Ze-Kuan Xu, Qing Du & Yi Miao

3. The First School of Clinical Medicine, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People’s Republic of China

   Kun-Ling Xie, Yun-Peng Peng, Jin-Qiu Tao, Jie Tang & Zheng Li

Authors

1. Jing-Jing ZhangView author publications

   You can also search for this author inPubMed Google Scholar

2. Yi ZhuView author publications

   You can also search for this author inPubMed Google Scholar

3. Kun-Ling XieView author publications

   You can also search for this author inPubMed Google Scholar

4. Yun-Peng PengView author publications

   You can also search for this author inPubMed Google Scholar

5. Jin-Qiu TaoView author publications

   You can also search for this author inPubMed Google Scholar

6. Jie TangView author publications

   You can also search for this author inPubMed Google Scholar

7. Zheng LiView author publications

   You can also search for this author inPubMed Google Scholar

8. Ze-Kuan XuView author publications

   You can also search for this author inPubMed Google Scholar

9. Cun-Cai DaiView author publications

   You can also search for this author inPubMed Google Scholar

10. Zhu-Yin QianView author publications

    You can also search for this author inPubMed Google Scholar

11. Kui-Rong JiangView author publications

    You can also search for this author inPubMed Google Scholar

12. Jun-Li WuView author publications

    You can also search for this author inPubMed Google Scholar

13. Wen-Tao GaoView author publications

    You can also search for this author inPubMed Google Scholar

14. Qing DuView author publications

    You can also search for this author inPubMed Google Scholar

15. Yi MiaoView author publications

    You can also search for this author inPubMed Google Scholar

Corresponding author

Correspondence to Yi Miao.

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Reprints and permissions

Cite this article

Zhang, JJ., Zhu, Y., Xie, KL. et al. Editorial expression of concern: Yin Yang-1 suppresses invasion and metastasis of pancreatic ductal adenocarcinoma by downregulating MMP10 in a MUC4/ErbB2/p38/MEF2C-dependent mechanism. Mol Cancer 24, 112 (2025). https://doi.org/10.1186/s12943-025-02326-6

Download citation

• Published: 14 April 2025

• DOI: https://doi.org/10.1186/s12943-025-02326-6

Share this article

Anyone you share the following link with will be able to read this content:

Get shareable link

Sorry, a shareable link is not currently available for this article.

Copy to clipboard

Provided by the Springer Nature SharedIt content-sharing initiative