碳纤维/芳纶高胫骨截骨弹性复合钢板生物力学及生物相容性研究

IF 2 3区医学 Q2 ORTHOPEDICS

Archives of Orthopaedic and Trauma Surgery Pub Date : 2025-04-10 DOI:10.1007/s00402-025-05857-1

Kun Xu, Daizhu Yuan, Zhanyu Wu, Yuhu Zhou, Jianxiang Teng, Chuan Ye

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引用次数: 0

摘要

目前，t形钛Tomofix接骨板是开楔高位胫骨截骨术（HTO）中最常用的内固定接骨板。但硬质钛合金板的弹性模量与人体皮质骨的弹性模量不匹配，造成较大的“应力屏蔽效应”。同时，HTO骨板具有一定的需求弹性。在本研究中，测试了碳纤维/凯夫拉复合材料板在不同编织（平纹/斜纹/ w纹/ i纹）和厚度下的弯曲、拉伸和压缩力学性能。采用有限元法对2.0 mm、2.5 mm和3.0 mm三种不同厚度的钛合金和碳纤维/Kevlar复合材料HTO骨板内固定后的生物力学结果进行分析比较，并通过细胞增殖试验和活/死染色活性分析考察其生物相容性。结果2.0 mm厚斜纹编织碳纤维/凯夫拉复合骨板的机械强度和韧性结合性能最佳，弹性模量为44.5 GPa。有限元模拟结果表明，2.0 mm厚斜纹碳纤维/凯夫拉弹性复合植骨板降低“应力屏蔽效应”的效果最好。此外，碳纤维/凯夫拉材料具有良好的生物相容性，不与溶血反应。结论2.0 mm斜纹编织碳纤维/凯夫拉弹性复合接骨板具有足够的强度和优异的韧性，其弹性模量与人体皮质骨更加兼容，充分满足HTO接骨板对弹性的特殊需求，同时以最佳效果降低“应力屏蔽效应”。因此，碳纤维/凯夫拉复合材料在HTO骨板的应用具有很大的潜力。

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Biomechanical and biocompatibility study of carbon fibre/kevlar high tibial osteotomy elastic composite plate

Introduction

Currently, the T-shaped titanium Tomofix bone plate is the most commonly used internal fixation bone plate in Open-wedge high tibial osteotomy (HTO). However, the modulus of elasticity of the hard titanium alloy plate does not match the modulus of elasticity of the human cortical bone, resulting in a large “stress shielding effect.” At the same time, HTO bone plates have a certain elasticity of demand.

Materials and methods

In this study, the classical mechanical properties of carbon fibre/Kevlar composite plates were tested in bending, tensile and compression with different weaves ((plain weave/twill weave/W-weave/I-weave) and thicknesses. The biomechanical results after internal fixation of titanium and carbon fibre/Kevlar composite HTO bone plates of three different thicknesses (2.0 mm, 2.5 mm, and 3.0 mm) were analyzed and compared using the finite element analysis (FEA) method, and their biocompatibility was investigated by the cell proliferation assay, and the analysis of live/dead staining activity.

Results

The combination of mechanical strength and toughness of the 2.0 mm thick twill weave carbon fibre/Kevlar composite bone plate showed the best performance and a modulus of elasticity of 44.5 GPa.The finite element simulation shows that the 2.0 mm thick twill carbon fibre/Kevlar elastic composite bone graft plate has the best effect in reducing the “stress shielding effect”. In addition, the carbon fibre/Kevlar material has good biocompatibility, and it does not react with hemolysis.

Conclusion

The 2.0 mm twill weave carbon fibre/Kevlar elastic composite bone plate has sufficient strength and excellent toughness, and its modulus of elasticity is more compatible with human cortical bone, which fully meets the special demand for elasticity of HTO bone plate and at the same time, reduces the “stress shielding effect” with the best effect. Therefore, carbon fibre/Kevlar composites have great potential in the application of HTO bone plates.

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来源期刊

Archives of Orthopaedic and Trauma Surgery 医学-外科

CiteScore

4.30

自引率

13.00%

发文量

424

审稿时长

2 months

期刊介绍： "Archives of Orthopaedic and Trauma Surgery" is a rich source of instruction and information for physicians in clinical practice and research in the extensive field of orthopaedics and traumatology. The journal publishes papers that deal with diseases and injuries of the musculoskeletal system from all fields and aspects of medicine. The journal is particularly interested in papers that satisfy the information needs of orthopaedic clinicians and practitioners. The journal places special emphasis on clinical relevance. "Archives of Orthopaedic and Trauma Surgery" is the official journal of the German Speaking Arthroscopy Association (AGA).