Pravin Panditrao Kalyankar, Ravivir Singh Bhalla, Deekshitha Alla, Nikhil Gupta, Srija Sirineni, Abhinav Vulisha, Mario Mekhail, Alla Sai Santhosha Mrudula, Ananth Rupesh Kattamreddy
{"title":"寻常型天疱疮患者罕见的利妥昔单抗诱导间质性肺疾病的表现。","authors":"Pravin Panditrao Kalyankar, Ravivir Singh Bhalla, Deekshitha Alla, Nikhil Gupta, Srija Sirineni, Abhinav Vulisha, Mario Mekhail, Alla Sai Santhosha Mrudula, Ananth Rupesh Kattamreddy","doi":"10.59556/japi.73.0916","DOIUrl":null,"url":null,"abstract":"<p><p>A 42-year-old female with a history of pemphigus vulgaris was started on rituximab after an inadequate response to corticosteroids. One month following the second cycle of rituximab, she developed acute interstitial pneumonia, which was linked to rituximab since a thorough workup revealed no evidence of an infectious cause. We initiated her on broad-spectrum intravenous (IV) antibiotics and antifungals, but the patient responded significantly to pulse methylprednisolone therapy.</p>","PeriodicalId":22693,"journal":{"name":"The Journal of the Association of Physicians of India","volume":"73 4","pages":"e55-e56"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rare Presentation of Rituximab-induced Interstitial Lung Disease in a Patient with Pemphigus Vulgaris.\",\"authors\":\"Pravin Panditrao Kalyankar, Ravivir Singh Bhalla, Deekshitha Alla, Nikhil Gupta, Srija Sirineni, Abhinav Vulisha, Mario Mekhail, Alla Sai Santhosha Mrudula, Ananth Rupesh Kattamreddy\",\"doi\":\"10.59556/japi.73.0916\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A 42-year-old female with a history of pemphigus vulgaris was started on rituximab after an inadequate response to corticosteroids. One month following the second cycle of rituximab, she developed acute interstitial pneumonia, which was linked to rituximab since a thorough workup revealed no evidence of an infectious cause. We initiated her on broad-spectrum intravenous (IV) antibiotics and antifungals, but the patient responded significantly to pulse methylprednisolone therapy.</p>\",\"PeriodicalId\":22693,\"journal\":{\"name\":\"The Journal of the Association of Physicians of India\",\"volume\":\"73 4\",\"pages\":\"e55-e56\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of the Association of Physicians of India\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.59556/japi.73.0916\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of the Association of Physicians of India","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.59556/japi.73.0916","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Rare Presentation of Rituximab-induced Interstitial Lung Disease in a Patient with Pemphigus Vulgaris.
A 42-year-old female with a history of pemphigus vulgaris was started on rituximab after an inadequate response to corticosteroids. One month following the second cycle of rituximab, she developed acute interstitial pneumonia, which was linked to rituximab since a thorough workup revealed no evidence of an infectious cause. We initiated her on broad-spectrum intravenous (IV) antibiotics and antifungals, but the patient responded significantly to pulse methylprednisolone therapy.