小儿中枢神经系统肿瘤放射治疗后的神经系统后遗症：综合综述

IF 2.4 4区医学 Q2 CLINICAL NEUROLOGY

Seminars in Pediatric Neurology Pub Date : 2025-04-01 DOI:10.1016/j.spen.2025.101181

Ritesh Kumar, Lakshmi Rekha Narra, Zohaib Sherwani, Rahul R Parikh

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引用次数: 0

摘要

放射治疗在小儿中枢神经系统（CNS）肿瘤的治疗中起着关键作用。然而，它对神经功能的潜在长期影响带来了重大挑战。在这篇综述中，我们研究了小儿中枢神经系统肿瘤幸存者的神经系统后遗症的范围，重点是临床表现、评估方法和管理策略。讨论的主要领域包括神经认知缺陷、内分泌功能障碍、脑血管并发症和继发性恶性肿瘤。重点是通过先进的放射治疗技术和综合生存护理来减轻辐射引起的毒性。

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Neurological sequalae in pediatric patients with CNS tumors after radiation treatment: A comprehensive review

Radiation therapy plays a pivotal role in treating pediatric central nervous system (CNS) tumors. However, its potential long-term impact on neurological function poses significant challenges. In this review, we examine the scope of neurological sequelae in survivors of pediatric CNS tumors, with a focus on clinical manifestations, evaluation methods, and management strategies. Key areas discussed include neurocognitive deficits, endocrine dysfunctions, cerebrovascular complications, and secondary malignancies. Emphasis is placed on mitigating radiation-induced toxicity through advanced radiotherapy techniques and integrated survivorship care.

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来源期刊

Seminars in Pediatric Neurology CLINICAL NEUROLOGY-PEDIATRICS

CiteScore

4.80

自引率

0.00%

发文量

审稿时长

84 days

期刊介绍： Seminars in Pediatric Neurology is a topical journal that focuses on subjects of current importance in the field of pediatric neurology. The journal is devoted to making the status of such topics and the results of new investigations readily available to the practicing physician. Seminars in Pediatric Neurology is of special interest to pediatric neurologists, pediatric neuropathologists, behavioral pediatricians, and neurologists who treat all ages.