编辑关注的表达:染色体9q22.3区域候选基因PHF2、FANCC、PTCH1和XPA的改变:早发性和晚发性乳腺癌的病理意义

IF 27.7 1区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
Satyabrata Sinha, Ratnesh K. Singh, Neyaz Alam, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda
{"title":"编辑关注的表达:染色体9q22.3区域候选基因PHF2、FANCC、PTCH1和XPA的改变:早发性和晚发性乳腺癌的病理意义","authors":"Satyabrata Sinha, Ratnesh K. Singh, Neyaz Alam, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda","doi":"10.1186/s12943-024-02181-x","DOIUrl":null,"url":null,"abstract":"<p><b>Correction: Mol Cancer 7, 84 (2008)</b></p><p><b>https://doi.org/10.1186/1476-4598-7-84</b>.</p><p> The Editor-in-Chief would like to alert the readers that concerns have been raised regarding some of the data presented in the figures. Specifically:</p><ul>\n<li>\n<p>In Fig. 1c (upper panel), the 588 T and 366 D9S104 bands appear highly similar, and the 4131 T D9S104 band appears highly similar to 3025 N PHF2 ex-18.</p>\n</li>\n<li>\n<p>In Fig. 3b, the two upper panels appear to have repetitive features in the gel backgrounds, and the bottom panel appears to have inconsistencies in the background.</p>\n</li>\n<li>\n<p>Figure 6c and f appear highly similar to Fig. 5d and a in [1], respectively.</p>\n</li>\n</ul><p> Due to the age of the article, the authors are unable to provide the underlying raw data to sufficiently address these concerns. Readers are therefore advised to interpret these results with caution.</p><p> All authors agree to this Editorial Expression of Concern.</p><ol data-track-component=\"outbound reference\" data-track-context=\"references section\"><li data-counter=\"1.\"><p>Sinha Satyabrata, Singh Ratnesh K, Nilanjana B, Nupur M, Susmita G, Neyaz A, Anup R, Susanta R, Chinmay Kumar P. Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognostic implications. Mol Oncol. 2011;5. https://doi.org/10.1016/j.molonc.2011.06.005.</p></li></ol><p>Download references<svg aria-hidden=\"true\" focusable=\"false\" height=\"16\" role=\"img\" width=\"16\"><use xlink:href=\"#icon-eds-i-download-medium\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"></use></svg></p><h3>Authors and Affiliations</h3><ol><li><p>Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India</p><p>Satyabrata Sinha, Ratnesh K. Singh &amp; Chinmay Kumar Panda</p></li><li><p>Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, India</p><p>Neyaz Alam</p></li><li><p>Department of Pathology, Medical College, Kolkata, India</p><p>Anup Roy</p></li><li><p>Molecular and Human Genetics Division, Indian Institute of Chemical Biology, Kolkata, India</p><p>Susanta Roychoudhury</p></li></ol><span>Authors</span><ol><li><span>Satyabrata Sinha</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Ratnesh K. Singh</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Neyaz Alam</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Anup Roy</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Susanta Roychoudhury</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Chinmay Kumar Panda</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li></ol><h3>Corresponding author</h3><p>Correspondence to Chinmay Kumar Panda.</p><h3>Publisher’s note</h3><p>Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.</p><p>The online version of the original article can be found at https://doi.org/10.1186/1476-4598-7-84.</p><p><b>Open Access</b> This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.</p>\n<p>Reprints and permissions</p><img alt=\"Check for updates. 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0-.92-.08-1.33-.25-.41-.16-.77-.4-1.08-.7-.3-.31-.54-.69-.72-1.13-.17-.44-.26-.95-.26-1.52zm4.61-.62c0-.55-.11-.98-.34-1.28-.23-.31-.58-.47-1.06-.47-.41 0-.77.15-1.08.45-.31.29-.5.73-.57 1.3zm3.01 2.23c.31.24.61.43.92.57.3.13.63.2.98.2.38 0 .65-.08.83-.23s.27-.35.27-.6c0-.14-.05-.26-.13-.37-.08-.1-.2-.2-.34-.28-.14-.09-.29-.16-.47-.23l-.53-.22c-.23-.09-.46-.18-.69-.3-.23-.11-.44-.24-.62-.4s-.33-.35-.45-.55c-.12-.21-.18-.46-.18-.75 0-.61.23-1.1.68-1.49.44-.38 1.06-.57 1.83-.57.48 0 .91.08 1.29.25s.71.36.99.57l-.74.98c-.24-.17-.49-.32-.73-.42-.25-.11-.51-.16-.78-.16-.35 0-.6.07-.76.21-.17.15-.25.33-.25.54 0 .14.04.26.12.36s.18.18.31.26c.14.07.29.14.46.21l.54.19c.23.09.47.18.7.29s.44.24.64.4c.19.16.34.35.46.58.11.23.17.5.17.82 0 .3-.06.58-.17.83-.12.26-.29.48-.51.68-.23.19-.51.34-.84.45-.34.11-.72.17-1.15.17-.48 0-.95-.09-1.41-.27-.46-.19-.86-.41-1.2-.68z" fill="#535353"/></g></svg>\" width=\"57\"/><h3>Cite this article</h3><p>Sinha, S., Singh, R.K., Alam, N. <i>et al.</i> Editorial Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma. <i>Mol Cancer</i> <b>24</b>, 108 (2025). https://doi.org/10.1186/s12943-024-02181-x</p><p>Download citation<svg aria-hidden=\"true\" focusable=\"false\" height=\"16\" role=\"img\" width=\"16\"><use xlink:href=\"#icon-eds-i-download-medium\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"></use></svg></p><ul data-test=\"publication-history\"><li><p>Published<span>: </span><span><time datetime=\"2025-04-05\">05 April 2025</time></span></p></li><li><p>DOI</abbr><span>: </span><span>https://doi.org/10.1186/s12943-024-02181-x</span></p></li></ul><h3>Share this article</h3><p>Anyone you share the following link with will be able to read this content:</p><button data-track=\"click\" data-track-action=\"get shareable link\" data-track-external=\"\" data-track-label=\"button\" type=\"button\">Get shareable link</button><p>Sorry, a shareable link is not currently available for this article.</p><p data-track=\"click\" data-track-action=\"select share url\" data-track-label=\"button\"></p><button data-track=\"click\" data-track-action=\"copy share url\" data-track-external=\"\" data-track-label=\"button\" type=\"button\">Copy to clipboard</button><p> Provided by the Springer Nature SharedIt content-sharing initiative </p>","PeriodicalId":19000,"journal":{"name":"Molecular Cancer","volume":"95 1","pages":""},"PeriodicalIF":27.7000,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Editorial Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma\",\"authors\":\"Satyabrata Sinha, Ratnesh K. Singh, Neyaz Alam, Anup Roy, Susanta Roychoudhury, Chinmay Kumar Panda\",\"doi\":\"10.1186/s12943-024-02181-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>Correction: Mol Cancer 7, 84 (2008)</b></p><p><b>https://doi.org/10.1186/1476-4598-7-84</b>.</p><p> The Editor-in-Chief would like to alert the readers that concerns have been raised regarding some of the data presented in the figures. Specifically:</p><ul>\\n<li>\\n<p>In Fig. 1c (upper panel), the 588 T and 366 D9S104 bands appear highly similar, and the 4131 T D9S104 band appears highly similar to 3025 N PHF2 ex-18.</p>\\n</li>\\n<li>\\n<p>In Fig. 3b, the two upper panels appear to have repetitive features in the gel backgrounds, and the bottom panel appears to have inconsistencies in the background.</p>\\n</li>\\n<li>\\n<p>Figure 6c and f appear highly similar to Fig. 5d and a in [1], respectively.</p>\\n</li>\\n</ul><p> Due to the age of the article, the authors are unable to provide the underlying raw data to sufficiently address these concerns. Readers are therefore advised to interpret these results with caution.</p><p> All authors agree to this Editorial Expression of Concern.</p><ol data-track-component=\\\"outbound reference\\\" data-track-context=\\\"references section\\\"><li data-counter=\\\"1.\\\"><p>Sinha Satyabrata, Singh Ratnesh K, Nilanjana B, Nupur M, Susmita G, Neyaz A, Anup R, Susanta R, Chinmay Kumar P. Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognostic implications. Mol Oncol. 2011;5. https://doi.org/10.1016/j.molonc.2011.06.005.</p></li></ol><p>Download references<svg aria-hidden=\\\"true\\\" focusable=\\\"false\\\" height=\\\"16\\\" role=\\\"img\\\" width=\\\"16\\\"><use xlink:href=\\\"#icon-eds-i-download-medium\\\" xmlns:xlink=\\\"http://www.w3.org/1999/xlink\\\"></use></svg></p><h3>Authors and Affiliations</h3><ol><li><p>Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India</p><p>Satyabrata Sinha, Ratnesh K. Singh &amp; Chinmay Kumar Panda</p></li><li><p>Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, India</p><p>Neyaz Alam</p></li><li><p>Department of Pathology, Medical College, Kolkata, India</p><p>Anup Roy</p></li><li><p>Molecular and Human Genetics Division, Indian Institute of Chemical Biology, Kolkata, India</p><p>Susanta Roychoudhury</p></li></ol><span>Authors</span><ol><li><span>Satyabrata Sinha</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Ratnesh K. Singh</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Neyaz Alam</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Anup Roy</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Susanta Roychoudhury</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Chinmay Kumar Panda</span>View author publications<p><span>You can also search for this author in</span><span>PubMed<span> </span>Google Scholar</span></p></li></ol><h3>Corresponding author</h3><p>Correspondence to Chinmay Kumar Panda.</p><h3>Publisher’s note</h3><p>Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.</p><p>The online version of the original article can be found at https://doi.org/10.1186/1476-4598-7-84.</p><p><b>Open Access</b> This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. 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Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma. <i>Mol Cancer</i> <b>24</b>, 108 (2025). https://doi.org/10.1186/s12943-024-02181-x</p><p>Download citation<svg aria-hidden=\\\"true\\\" focusable=\\\"false\\\" height=\\\"16\\\" role=\\\"img\\\" width=\\\"16\\\"><use xlink:href=\\\"#icon-eds-i-download-medium\\\" xmlns:xlink=\\\"http://www.w3.org/1999/xlink\\\"></use></svg></p><ul data-test=\\\"publication-history\\\"><li><p>Published<span>: </span><span><time datetime=\\\"2025-04-05\\\">05 April 2025</time></span></p></li><li><p>DOI</abbr><span>: </span><span>https://doi.org/10.1186/s12943-024-02181-x</span></p></li></ul><h3>Share this article</h3><p>Anyone you share the following link with will be able to read this content:</p><button data-track=\\\"click\\\" data-track-action=\\\"get shareable link\\\" data-track-external=\\\"\\\" 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更正:Mol巨蟹座7,84 (2008)https://doi.org/10.1186/1476-4598-7-84。总编辑想提醒读者,人们对图表中的一些数据提出了担忧。具体而言:在图1c(上面板)中,588 T和366 D9S104波段高度相似,4131 T D9S104波段与3025 N PHF2 ex-18高度相似。在图3b中,上面两个面板在凝胶背景中似乎具有重复的特征,而底部面板在背景中似乎具有不一致的特征。图6c和图f分别与[1]中的图5d和图a非常相似。由于文章的年龄,作者无法提供潜在的原始数据来充分解决这些问题。因此,建议读者谨慎解读这些结果。所有作者都同意这一编辑关注表达。Sinha Satyabrata, Singh ratneesh K, Nilanjana B, Nupur M, Susmita G, Neyaz A, Anup R, Susanta R, Chinmay Kumar P.乳腺癌11q24.1-24.2区LOH11CR2A、PIG8和CHEK1基因的频繁改变:临床和预后意义。4 .中华医学杂志,2011;https://doi.org/10.1016/j.molonc.2011.06.005.Download作者与联系印度加尔各答Chittaranjan国家癌症研究所癌基因调控部atyabrata Sinha, Ratnesh K. Singh &;Chinmay Kumar panda印度加尔各答Chittaranjan国家癌症研究所外科肿瘤科;neyaz alam印度加尔各答医学院病理学系;anup roya印度化学生物学研究所分子与人类遗传学部;indiasanta RoychoudhuryAuthorsSatyabrata SinhaView作者出版物您也可以在pubmed谷歌ScholarRatnesh K. SinghView作者出版物您也可以在pubmed谷歌ScholarNeyaz AlamView作者出版物中搜索该作者您也可以在pubmed谷歌ScholarAnup RoyView作者出版物中搜索该作者您也可以在pubmed谷歌ScholarSusanta RoychoudhuryView作者出版物中搜索该作者您也可以在pubmed谷歌scholaranta RoychoudhuryView作者出版物中搜索该作者您也可以搜索该作者inPubMed谷歌ScholarChinmay Kumar PandaView作者出版物您也可以在pubmed谷歌scholar.com中搜索该作者。出版方声明:对于已出版地图的管辖权要求和机构关系,普林格·自然保持中立。本文遵循知识共享署名-非商业-非衍生品4.0国际许可协议,该协议允许以任何媒介或格式进行非商业用途、共享、分发和复制,只要您适当地注明原作者和来源,并提供知识共享许可协议的链接。并注明你是否修改了授权材料。根据本许可协议,您无权分享源自本文或其部分内容的改编材料。本文中的图像或其他第三方材料包含在文章的知识共享许可协议中,除非在材料的署名中另有说明。如果材料未包含在文章的知识共享许可中,并且您的预期用途不被法律法规允许或超过允许的用途,您将需要直接获得版权所有者的许可。要查看本许可证的副本,请访问http://creativecommons.org/licenses/by-nc-nd/4.0/.Reprints和permissionsCite本文inha, S., Singh, r.k., Alam, N.等人。编辑关注的表达:染色体9q22.3区域候选基因PHF2、FANCC、PTCH1和XPA的改变:早发性和晚发性乳腺癌的病理意义。癌症学报,24(5):2023 - 2023。https://doi.org/10.1186/s12943-024-02181-xDownload citationpublishing: 05 April 2025DOI: https://doi.org/10.1186/s12943-024-02181-xShare这篇文章任何你分享以下链接的人都可以阅读到这篇文章:获取可共享链接对不起,这篇文章目前没有可共享链接。复制到剪贴板由施普林格自然共享内容倡议提供
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Editorial Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma

Correction: Mol Cancer 7, 84 (2008)

https://doi.org/10.1186/1476-4598-7-84.

The Editor-in-Chief would like to alert the readers that concerns have been raised regarding some of the data presented in the figures. Specifically:

  • In Fig. 1c (upper panel), the 588 T and 366 D9S104 bands appear highly similar, and the 4131 T D9S104 band appears highly similar to 3025 N PHF2 ex-18.

  • In Fig. 3b, the two upper panels appear to have repetitive features in the gel backgrounds, and the bottom panel appears to have inconsistencies in the background.

  • Figure 6c and f appear highly similar to Fig. 5d and a in [1], respectively.

Due to the age of the article, the authors are unable to provide the underlying raw data to sufficiently address these concerns. Readers are therefore advised to interpret these results with caution.

All authors agree to this Editorial Expression of Concern.

  1. Sinha Satyabrata, Singh Ratnesh K, Nilanjana B, Nupur M, Susmita G, Neyaz A, Anup R, Susanta R, Chinmay Kumar P. Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognostic implications. Mol Oncol. 2011;5. https://doi.org/10.1016/j.molonc.2011.06.005.

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Authors and Affiliations

  1. Department of Oncogene Regulation, Chittaranjan National Cancer Institute, Kolkata, India

    Satyabrata Sinha, Ratnesh K. Singh & Chinmay Kumar Panda

  2. Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, India

    Neyaz Alam

  3. Department of Pathology, Medical College, Kolkata, India

    Anup Roy

  4. Molecular and Human Genetics Division, Indian Institute of Chemical Biology, Kolkata, India

    Susanta Roychoudhury

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  1. Satyabrata SinhaView author publications

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Correspondence to Chinmay Kumar Panda.

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Sinha, S., Singh, R.K., Alam, N. et al. Editorial Expression of Concern: Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma. Mol Cancer 24, 108 (2025). https://doi.org/10.1186/s12943-024-02181-x

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来源期刊
Molecular Cancer
Molecular Cancer 医学-生化与分子生物学
CiteScore
54.90
自引率
2.70%
发文量
224
审稿时长
2 months
期刊介绍: Molecular Cancer is a platform that encourages the exchange of ideas and discoveries in the field of cancer research, particularly focusing on the molecular aspects. Our goal is to facilitate discussions and provide insights into various areas of cancer and related biomedical science. We welcome articles from basic, translational, and clinical research that contribute to the advancement of understanding, prevention, diagnosis, and treatment of cancer. The scope of topics covered in Molecular Cancer is diverse and inclusive. These include, but are not limited to, cell and tumor biology, angiogenesis, utilizing animal models, understanding metastasis, exploring cancer antigens and the immune response, investigating cellular signaling and molecular biology, examining epidemiology, genetic and molecular profiling of cancer, identifying molecular targets, studying cancer stem cells, exploring DNA damage and repair mechanisms, analyzing cell cycle regulation, investigating apoptosis, exploring molecular virology, and evaluating vaccine and antibody-based cancer therapies. Molecular Cancer serves as an important platform for sharing exciting discoveries in cancer-related research. It offers an unparalleled opportunity to communicate information to both specialists and the general public. The online presence of Molecular Cancer enables immediate publication of accepted articles and facilitates the presentation of large datasets and supplementary information. This ensures that new research is efficiently and rapidly disseminated to the scientific community.
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