探讨立体定向放射治疗在癌症治疗中的当前挑战和开创性临床应用。

IF 2.8 4区 医学 Q3 ONCOLOGY
Technology in Cancer Research & Treatment Pub Date : 2025-01-01 Epub Date: 2025-04-03 DOI:10.1177/15330338251333658
Atsuto Katano
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引用次数: 0

摘要

立体定向放射治疗(SRT)已成为现代肿瘤学不可或缺的一部分,提供了提供消融剂量的能力,同时最大限度地减少对周围正常组织的损害。在影像整合、治疗计划和剂量传递方面的最新进展扩大了其在各种肿瘤类型中的临床应用。然而,诸如解剖关键区域的毒性、最佳边缘确定以及缺乏标准化方案等挑战仍然存在。本综述探讨了当代实践中的关键问题,并强调了肺、肝、前列腺、脑和少转移性疾病的新临床证据。进一步完善患者选择和治疗策略对于最大限度地提高治疗效果和确保在更广泛的临床环境中安全实施至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring the Current Challenges and Pioneering Clinical Applications of Stereotactic Radiotherapy in Cancer Treatment.

Stereotactic radiotherapy (SRT) has become integral to modern oncology, offering the ability to deliver ablative doses while minimizing damage to surrounding normal tissues. Recent advancements in imaging integration, treatment planning, and dose delivery have expanded their clinical applications across various tumor types. However, challenges such as toxicity in anatomically critical regions, optimal margin determination, and the lack of standardized protocols persist. This review explores key issues in contemporary practice and highlights emerging clinical evidence across lung, liver, prostate, brain, and oligometastatic diseases. Further refinement in patient selection and treatment strategies is essential to maximize therapeutic efficacy and ensure safe implementation in broader clinical settings.

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来源期刊
CiteScore
4.40
自引率
0.00%
发文量
202
审稿时长
2 months
期刊介绍: Technology in Cancer Research & Treatment (TCRT) is a JCR-ranked, broad-spectrum, open access, peer-reviewed publication whose aim is to provide researchers and clinicians with a platform to share and discuss developments in the prevention, diagnosis, treatment, and monitoring of cancer.
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