对通过腘绳肌腱自体移植进行前交叉韧带重建的患者进行为期四周的北欧式腘绳肌锻炼干预:随机对照试验的可行性。

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Grant E Norte, Neal R Glaviano, David A Sherman, Justin L Rush, Amanda M Murray
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引用次数: 0

摘要

背景:北欧腘绳肌运动(NHE)已被广泛应用于未受伤的运动人群中,以减轻腘绳肌损伤的风险,但对于使用腘绳肌腱自体移植(ACLR-HT)进行前交叉韧带重建的个体,其干预作用知之甚少。了解NHE作为一种增强腿筋功能的方法的可行性,可能有助于制定循证建议来指导腿筋恢复。我们的目的是确定在ACLR-HT患者中进行NHE试点试验的可行性。方法:我们采用单盲随机对照试验,平行对照研究18-35岁原发性单侧ACLR-HT患者。23名参与者按3:1的比例随机分为标准化的4周(10个疗程)渐进式NHE干预组(n = 17)或常规护理对照组(n = 6)。随机分配到对照组的患者在原始研究期结束时有资格进入干预组。主要可行性结果包括招募吸收、方案依从性、剂量目标实现和保留。运动认知和安全性也被评估。总结统计用于描述性地报告所有发现。结果:2名对照组受试者在完成原始研究期后进入干预组(n = 19)。所有参与者(88.5%)都遵守了运动方案(100%),18名参与者(94.7%)达到了总运动剂量目标。观察到100%的保留率,因为所有参与者(干预17随机,2开放入组;对照组6)返回进行随访评估。结论:对于ACLR-HT患者,标准化的4周渐进式NHE方案是可行的。积极的运动认知、最小的运动相关不适和无不良事件报告进一步支持了该方案的可接受性以及在未来疗效试验中成功实施的可能性。试验注册:ClinicalTrials.gov, NCT05738200。注册于2022年11月2日-追溯注册,https://clinicaltrials.gov/study/NCT05738200。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Four-week Nordic hamstring exercise intervention for individuals with ACL reconstruction via hamstrings tendon autograft: feasibility of a pilot randomized controlled trial.

Four-week Nordic hamstring exercise intervention for individuals with ACL reconstruction via hamstrings tendon autograft: feasibility of a pilot randomized controlled trial.

Background: The Nordic hamstring exercise (NHE) has been widely used among uninjured, athletic populations to mitigate the risk of hamstring injury, yet little is known about its utility as an intervention for individuals who undergo ACL reconstruction with hamstring tendon autograft (ACLR-HT). Understanding the feasibility of NHE as a means of enhancing hamstring function may aid in the development of evidence-based recommendations to guide hamstring recovery. Our aim was to determine the feasibility of conducting a pilot NHE trial among individuals with ACLR-HT.

Methods: We used a single-blind randomized controlled trial with parallel arms to investigate individuals 18-35 years with primary, unilateral ACLR-HT. Twenty-three participants were randomized to a standardized, 4-week (10 session) progressive NHE intervention (n = 17) or usual care control (n = 6) group at a 3:1 ratio. Those randomized to the control group were eligible to open-enroll in the intervention group at the completion of the original study period. Primary feasibility outcomes included recruitment uptake, protocol adherence, dose goal attainment, and retention. Exercise perceptions and safety were also assessed. Summary statistics were used to descriptively report all findings.

Results: Two control participants were open-enrolled in the intervention group after completing their original study period (n = 19). All participants (88.5% recruitment uptake) adhered to the exercise protocol (100%) and 18 participants (94.7%) attained the total exercise dosage goal. A 100% retention rate was observed, as all participants (intervention 17 randomized, 2 open-enrolled; control 6) returned for their follow-up assessment.

Conclusions: A standardized, 4-week progressive NHE protocol is feasible for individuals with ACLR-HT. Positive perceptions of exercise, minimal exercise-related discomfort, and no reported adverse events further support the acceptability of this protocol and the likelihood of successful implementation in future efficacy trials.

Trial registration: ClinicalTrials.gov, NCT05738200. Registered 2 November 2022-retrospectively registered, https://clinicaltrials.gov/study/NCT05738200 .

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来源期刊
Pilot and Feasibility Studies
Pilot and Feasibility Studies Medicine-Medicine (miscellaneous)
CiteScore
2.70
自引率
5.90%
发文量
241
审稿时长
9 weeks
期刊介绍: Pilot and Feasibility Studies encompasses all aspects of the design, conduct and reporting of pilot and feasibility studies in biomedicine. The journal publishes research articles that are intended to directly influence future clinical trials or large scale observational studies, as well as protocols, commentaries and methodology articles. The journal also ensures that the results of all well-conducted, peer-reviewed, pilot and feasibility studies are published, regardless of outcome or significance of findings. Pilot and feasibility studies are increasingly conducted prior to a full randomized controlled trial. However, these studies often lack clear objectives, many remain unpublished, and there is confusion over the meanings of the words “pilot” and “feasibility”. Pilot and Feasibility Studies provides a forum for discussion around this key aspect of the scientific process, and seeks to ensure that these studies are published, so as to complete the publication thread for clinical research.
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