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引用次数: 0
摘要
补体系统对于维持肝脏的免疫稳态至关重要，在先天和适应性免疫反应中都起着重要作用。该系统的失调与各种肝脏疾病的发病机制密切相关。调节补体系统可以影响这些疾病的进展。为了进一步研究如何通过调节补体系统来治疗肝损伤，我们对MEDLINE、PubMed、EMBASE和Web of Science等主要生物医学数据库进行了全面检索，收集了有关补体和肝损伤的文章，并对补体系统在肝损伤中的作用和机制进行了综述。
Research progress on the roles of complement in liver injury.
The complement system is crucial for maintaining immunological homeostasis in the liver, playing a significant role in both innate and adaptive immune responses. Dysregulation of this system is closely linked to the pathogenesis of various liver diseases. Modulating the complement system can affect the progression of these conditions. To provide insights into treating liver injury by targeting the regulation of the complement system, we conducted a comprehensive search of major biomedical databases, including MEDLINE, PubMed, EMBASE, and Web of Science, to identify articles on complement and liver injury and reviewed the functions and mechanisms of the complement system in liver injury.
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