现代药物发现的基本数据库资源。

Q1 Pharmacology, Toxicology and Pharmaceutics
Advances in pharmacology Pub Date : 2025-01-01 Epub Date: 2025-02-08 DOI:10.1016/bs.apha.2025.01.002
Saloni Yadav, Sweta S Koka, Priya Jain, G N Darwhekar, Kuldeep Vinchurkar
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引用次数: 0

摘要

在快速发展的药物发现领域,研究人员和制药专业人员需要立即访问关键的数据库资源。这本书的章节解释了在药物开发的各个阶段使用的基本数据库,如目标选择,化学筛选和临床试验管理。包括PubChem, ChEMBL和Drug Bank在内的数据库突出了它们在提供详细的化学知识,生物活性数据和药物相互作用概况方面的贡献。使用强大的计算机程序,如人工智能和机器学习,将来自这些来源的数据结合起来,可以改善决策,加快上市时间,并提高发现有效药物的机会。本章标志着关键数据库的重要性,他们的用途,以及他们如何融入当前的药物发现过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Essential database resources for modern drug discovery.

In the fast-expanding field of drug discovery, researchers and pharmaceutical professionals require immediate access to critical database resources. This book chapter explains essential databases used in various stages of drug development, such as target selection, chemical screening, and clinical trial management. Databases including PubChem, ChEMBL, and Drug Bank, highlight their contributions to providing detailed chemical knowledge, biological activity data, and drug interaction profiles. Using powerful computer programs like AI and machine learning to combine data from these sources improves decision-making, speeds up time-to-market, and raises the chances of finding effective medicines. This book chapter signifies the importance of key databases, their uses, and how they integrate into the current drug discovery process.

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来源期刊
Advances in pharmacology
Advances in pharmacology Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
9.10
自引率
0.00%
发文量
45
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