Prediction of IUGR condition at birth by means of CTG recordings and a ResNet model

Objective

Sub-optimal uterine-placental perfusion and fetal nutrition can lead to intrauterine growth restriction (IUGR), also called fetal growth restriction (FGR). Antenatal cardiotocography (CTG) can aid in the early detection of IUGR. Reliably diagnosing IUGR before delivery remains challenging, and deep learning (DL) techniques offer potential solutions. This paper describes the development of a DL approach to predict an IUGR condition at birth by using CTG signals collected during antenatal monitoring.

Materials and methods

Our method is encapsulated in the concept of a two-step training process of a ResNet architecture. The primary focus is on the minimization of data loss, which motivates the division into “presumed” and “confirmed” datasets, which is employed to distinguish based on the presence of information at birth. The method involves fine-tuning: the initial training utilizes “presumed” data to train the network, and the subsequent training employs data representing certain knowledge to refine its performance.

Results

The DL model reaches a balanced accuracy of 80% on a hold-out test set of confirmed cases, which is better than what obtained by using standard clinical guidelines.

Discussion

The results of our work are compared to the results of similar papers dealing with the prediction of IUGR condition at birth and in general with the prediction of fetal pathological conditions. Our final results are obtained using a very large dataset compared to other papers reported in the literature.

Conclusion

The inclusion of DL methods on CTG signals may complement imaging technologies and improve the early detection of IUGR.