精神分裂症患者PANSS Marder因子解决方案和其他因子模型的COSMIN综述。

IF 4.1 Q2 PSYCHIATRY
Maximilian Roithmeier, Simon Geck, Markus Bühner, Sophia Wehr, Lucia Weigel, Josef Priller, John M Davis, Stefan Leucht
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引用次数: 0

摘要

阳性和阴性症状量表(PANSS)被广泛用于评估精神分裂症的症状。Marder等人于1997年首次提出的5因子模型(M5M)最初设计为三个子量表,经常用于治疗试验,但其测量特性从未被系统地审查过。我们采用基于共识的健康测量工具选择标准(COSMIN)指南进行系统评价和元分析程序来评估M5M-PANSS的心理测量特性。COSMIN包括几个步骤:文献检索、偏倚风险评估、评估良好测量特性的最新标准、可行性方面和对证据质量进行分级。我们进一步评估了其他PANSS因子模型的拟合优度。我们纳入了95份出版物。M5M-PANSS的结构效度较好,但结构效度“不足”。其他宇宙域的证据很大程度上是缺乏的。在验证性方法检验的多(73)个因素解决方案中,其他几个5因素解决方案具有更好的模型拟合。根据COSMIN的规定,M5M不应被推荐使用。其他五因素模型(如Wallwork等人提出的模型)值得进一步评估。然而,M5M与其他模型的因子组成相对相似,因此不应忽视先前发表的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COSMIN review of the PANSS Marder factor solution and other factor models in people with schizophrenia.

The Positive and Negative Syndrome Scale (PANSS) is widely used to assess schizophrenia symptoms. Initially designed with three subscales, Marder et al.´s 5-factor-Model (M5M) first proposed in 1997 has been frequently used in treatment trials, but it has never been systematically reviewed for its measurement properties. We utilized the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guideline for systematic reviews and meta-analytical procedures to assess the psychometric properties of the M5M-PANSS. COSMIN comprises several steps: literature search, risk-of-bias assessments, assessing the updated criteria for good measurement properties, feasibility aspects and grading the quality of the evidence. We further assessed the goodness of fit of other PANSS factor models. We included 95 publications. The M5M-PANSS showed good construct validity, but "insufficient" structural validity. Evidence of other COSMIN domains is largely lacking. Among the multiple (73) factor solutions examined with confirmatory methods, several other 5-factor solutions had better model fit. According to COSMIN rules the M5M should not be recommended for use. Other five-factor models such as the one proposed by Wallwork et al.1 warrant further evaluation. Nevertheless, the factor composition of the M5M and these other models was relatively similar, so previously published results should not be disregarded.

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