经口食道延伸术作为终末期贲门失弛缓症伴肺泡形成的治疗选择。

IF 2.6 3区医学

Diseases of the Esophagus Pub Date : 2025-03-03 DOI:10.1093/dote/doaf013

Ryan G Alexander, Louis M Wong Kee Song, Avinash K Nehra, Jeffrey A Alexander, Don C Codipilly, Shanda H Blackmon, Karthik Ravi

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引用次数: 0

摘要

简介：食管口周成形术（POPE）可缩小终末期贲门失弛缓症患者的食管底盘并改善症状。然而，其长期疗效和安全性尚不清楚：方法：对在我院接受 POPE 治疗的终末期贲门失弛缓症患者（2016-2024 年）进行鉴定。结果：12 名患者接受了 POPE：12名患者接受了POPE手术。技术成功率为100%，平均手术时间为57分钟，无不良事件发生。75%的患者症状有所改善（平均随访时间为15个月），86%的患者底盘大小在影像学上有所改善。6 名患者（50%）在首次 POPE 平均 2.6 年后再次进行了 POPE，4 名患者（33%）在第三次 POPE 平均 3.1 年后再次进行了 POPE，其技术成功率和结果与首次 POPE 相似：POPE是治疗终末期贲门失弛缓症的一种安全、可重复的长期治疗方案。

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Peroral plication of the esophagus as a treatment option for end-stage achalasia with sump formation.

Introduction: Peroral plication of the esophagus (POPE) can reduce sump size and improve symptoms in end-stage achalasia. However, its long-term efficacy and safety are unknown.

Methods: Patients with end-stage achalasia who underwent POPE at our institution (2016-2024) were identified. Data were abstracted for patient demographics, procedural details, and clinical and radiographic outcomes.

Results: Twelve patients underwent POPE. The technical success rate was 100%, with mean procedural time of 57 minutes and without adverse events. Symptomatic improvement occurred in 75% of patients (mean follow-up of 15 months), while 86% had radiographic improvement in sump size. Repeat POPE in 6 (50%) patients a mean of 2.6 years after index POPE and a third POPE in four (33%) patients a mean of 3.1 years later was performed, with similar technical success rates and outcomes to the index POPE.

Conclusions: POPE is a safe and repeatable long-term therapeutic option in end-stage achalasia.

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来源期刊

Diseases of the Esophagus Medicine-Gastroenterology

自引率

7.70%

发文量

568

期刊介绍： Diseases of the Esophagus covers all aspects of the esophagus - etiology, investigation and diagnosis, and both medical and surgical treatment.