{"title":"FocusAugMix:一种增强急性淋巴细胞白血病分类的数据增强方法","authors":"Tanzilal Mustaqim , Chastine Fatichah , Nanik Suciati , Takashi Obi , Joong-Sun Lee","doi":"10.1016/j.iswa.2025.200512","DOIUrl":null,"url":null,"abstract":"<div><div>The detection of various subtypes of Acute Lymphoblastic Leukemia (ALL) is crucial for precise medical identification, even though it is often hindered by the diverse appearance of leukemia cells and limited medical resources. Challenges arise from the subjectivity of evaluations and constraints in datasets, impacting the accuracy of classification. Existing methods face difficulties in achieving precise localization and building robust classification models due to the complexities in morphology and variations in subtypes, leading to challenges in accurate classification. This research proposes the FocusAugMix, a novel data augmentation method based on superpixels, which integrates Gradient-weighted Class Activation Mapping (Grad-CAM), Multi-Head Attention, and SaliencyMix to improve classification performance, especially in situations with limited datasets. The dynamic selection of superpixel contour images for each images allows this method to achieve a peak accuracy of 99.07 %, surpassing the previous method. Integrating Multi-Head Attention and Grad-CAM improves the accuracy and effectiveness of class representation in data augmentation methods for medical diagnosis.</div></div>","PeriodicalId":100684,"journal":{"name":"Intelligent Systems with Applications","volume":"26 ","pages":"Article 200512"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"FocusAugMix: A data augmentation method for enhancing Acute Lymphoblastic Leukemia classification\",\"authors\":\"Tanzilal Mustaqim , Chastine Fatichah , Nanik Suciati , Takashi Obi , Joong-Sun Lee\",\"doi\":\"10.1016/j.iswa.2025.200512\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The detection of various subtypes of Acute Lymphoblastic Leukemia (ALL) is crucial for precise medical identification, even though it is often hindered by the diverse appearance of leukemia cells and limited medical resources. Challenges arise from the subjectivity of evaluations and constraints in datasets, impacting the accuracy of classification. Existing methods face difficulties in achieving precise localization and building robust classification models due to the complexities in morphology and variations in subtypes, leading to challenges in accurate classification. This research proposes the FocusAugMix, a novel data augmentation method based on superpixels, which integrates Gradient-weighted Class Activation Mapping (Grad-CAM), Multi-Head Attention, and SaliencyMix to improve classification performance, especially in situations with limited datasets. The dynamic selection of superpixel contour images for each images allows this method to achieve a peak accuracy of 99.07 %, surpassing the previous method. Integrating Multi-Head Attention and Grad-CAM improves the accuracy and effectiveness of class representation in data augmentation methods for medical diagnosis.</div></div>\",\"PeriodicalId\":100684,\"journal\":{\"name\":\"Intelligent Systems with Applications\",\"volume\":\"26 \",\"pages\":\"Article 200512\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Intelligent Systems with Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2667305325000389\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Intelligent Systems with Applications","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667305325000389","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
急性淋巴细胞白血病(Acute Lymphoblastic Leukemia, ALL)的各种亚型的检测对于精确的医学鉴定至关重要,尽管它经常受到白血病细胞多样外观和有限医疗资源的阻碍。挑战来自于评估的主观性和数据集的约束,影响了分类的准确性。由于形态的复杂性和亚型的多样性,现有的方法在实现精确定位和建立鲁棒分类模型方面存在困难,这给准确分类带来了挑战。本研究提出了一种新的基于超像素的数据增强方法FocusAugMix,该方法集成了梯度加权类激活映射(Gradient-weighted Class Activation Mapping, Grad-CAM)、多头注意(Multi-Head Attention)和SaliencyMix,以提高分类性能,特别是在数据集有限的情况下。每幅图像的超像素轮廓图像的动态选择使该方法达到99.07%的峰值精度,超过了以前的方法。将head - head Attention和Grad-CAM相结合,提高了医学诊断数据增强方法中类表示的准确性和有效性。
FocusAugMix: A data augmentation method for enhancing Acute Lymphoblastic Leukemia classification
The detection of various subtypes of Acute Lymphoblastic Leukemia (ALL) is crucial for precise medical identification, even though it is often hindered by the diverse appearance of leukemia cells and limited medical resources. Challenges arise from the subjectivity of evaluations and constraints in datasets, impacting the accuracy of classification. Existing methods face difficulties in achieving precise localization and building robust classification models due to the complexities in morphology and variations in subtypes, leading to challenges in accurate classification. This research proposes the FocusAugMix, a novel data augmentation method based on superpixels, which integrates Gradient-weighted Class Activation Mapping (Grad-CAM), Multi-Head Attention, and SaliencyMix to improve classification performance, especially in situations with limited datasets. The dynamic selection of superpixel contour images for each images allows this method to achieve a peak accuracy of 99.07 %, surpassing the previous method. Integrating Multi-Head Attention and Grad-CAM improves the accuracy and effectiveness of class representation in data augmentation methods for medical diagnosis.