全身性血管炎：回顾2025年一年。

IF 3.4 4区医学 Q2 RHEUMATOLOGY

Clinical and experimental rheumatology Pub Date : 2025-04-01 Epub Date: 2025-03-25 DOI:10.55563/clinexprheumatol/oyqz1p

Paolo Delvino, Chiara Baldini, Martina Bonacini, Stefania Croci, Federica Di Cianni, Francesco Ferro, Chiara Marvisi, Sara Monti, Michele Moretti, Francesco Muratore, Ludovica Pisapia, Caterina Ricordi, Antonello Sulis, Rosaria Talarico, Elena Treppo, Luca Quartuccio, Carlo Salvarani

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引用次数: 0

摘要

全身性血管病包括一系列影响多个器官和地区的炎症性疾病，对发病率和死亡率有重要影响。这篇年度综述提供了血管炎研究的最新进展，包括新兴的生物标志物，对发病机制的新见解，以及大血管和小血管炎的治疗创新。特别关注新兴概念，包括细胞衰老和基质细胞在血管炎症中的作用，单器官血管炎的范围扩大，以及越来越多地认识到VEXAS综合征是血管炎相关实体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Systemic vasculitis: one year in review 2025.

Systemic vasculitides encompass a spectrum of inflammatory disorders affecting several organs and districts, with significant implications for morbidity and mortality. This annual review provides an updated overview of key advancements in vasculitis research, including emerging biomarkers, novel insights into pathogenesis, and therapeutic innovations in both large and small vessel vasculitis. Particular attention is given to emerging concepts, including the role of cellular senescence and stromal cells in vascular inflammation, the expanding spectrum of single-organ vasculitis, and the growing recognition of VEXAS syndrome as a vasculitis-related entity.

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来源期刊

Clinical and experimental rheumatology 医学-风湿病学

CiteScore

6.10

自引率

18.90%

发文量

377

审稿时长

3-6 weeks

期刊介绍： Clinical and Experimental Rheumatology is a bi-monthly international peer-reviewed journal which has been covering all clinical, experimental and translational aspects of musculoskeletal, arthritic and connective tissue diseases since 1983.