{"title":"表达关切：H2S 供体西地那非（ACS6）抑制动脉内皮细胞中超氧化物的形成和 gp91phox 的表达：蛋白激酶 A 和 G 的作用。","authors":"","doi":"10.1111/bph.70041","DOIUrl":null,"url":null,"abstract":"<p><b>EXPRESSION OF CONCERN</b>: S. Muzaffar, J. Y. Jeremy, A. Sparatore, P. Del Soldato, G. D. Angelini, and N. Shukla, “H<sub>2</sub>S-Donating Sildenafil (ACS6) Inhibits Superoxide Formation and gp91<sup>phox</sup> Expression in Arterial Endothelial Cells: Role of Protein Kinases A and G,” <i>British Journal of Pharmacology</i> 155, no. 7 (2008): 984–994, https://doi.org/10.1038/bjp.2008.326.</p><p>This Expression of Concern is for the above article, published online on 29 January 2009 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by the journal Editor-in-Chief, Péter Ferdinandy; the British Pharmacological Society; and John Wiley & Sons Ltd.</p><p>The Expression of Concern has been agreed following an investigation by the journal after publication of concerns regarding the similarity of a blot in Figure 8 with one published elsewhere, and regarding the underlying data that it represents. The authors were unable to provide a satisfactory explanation and could not provide the original data given the time that had elapsed. However, the journal is issuing this Expression of Concern because the concerns regarding the integrity of the data and the results presented cannot be resolved.</p><p>Author G. D. A. agreed to this Expression of Concern.</p>","PeriodicalId":9262,"journal":{"name":"British Journal of Pharmacology","volume":"182 10","pages":"2332"},"PeriodicalIF":6.8000,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bph.70041","citationCount":"0","resultStr":"{\"title\":\"EXPRESSION OF CONCERN: H2S-Donating Sildenafil (ACS6) Inhibits Superoxide Formation and gp91phox Expression in Arterial Endothelial Cells: Role of Protein Kinases A and G\",\"authors\":\"\",\"doi\":\"10.1111/bph.70041\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>EXPRESSION OF CONCERN</b>: S. Muzaffar, J. Y. Jeremy, A. Sparatore, P. Del Soldato, G. D. Angelini, and N. Shukla, “H<sub>2</sub>S-Donating Sildenafil (ACS6) Inhibits Superoxide Formation and gp91<sup>phox</sup> Expression in Arterial Endothelial Cells: Role of Protein Kinases A and G,” <i>British Journal of Pharmacology</i> 155, no. 7 (2008): 984–994, https://doi.org/10.1038/bjp.2008.326.</p><p>This Expression of Concern is for the above article, published online on 29 January 2009 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by the journal Editor-in-Chief, Péter Ferdinandy; the British Pharmacological Society; and John Wiley & Sons Ltd.</p><p>The Expression of Concern has been agreed following an investigation by the journal after publication of concerns regarding the similarity of a blot in Figure 8 with one published elsewhere, and regarding the underlying data that it represents. The authors were unable to provide a satisfactory explanation and could not provide the original data given the time that had elapsed. However, the journal is issuing this Expression of Concern because the concerns regarding the integrity of the data and the results presented cannot be resolved.</p><p>Author G. D. A. agreed to this Expression of Concern.</p>\",\"PeriodicalId\":9262,\"journal\":{\"name\":\"British Journal of Pharmacology\",\"volume\":\"182 10\",\"pages\":\"2332\"},\"PeriodicalIF\":6.8000,\"publicationDate\":\"2025-03-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/bph.70041\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British Journal of Pharmacology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/bph.70041\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Journal of Pharmacology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/bph.70041","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
摘要
[j] .， J. Y. Jeremy， A. Sparatore， P. Del Soldato， G. D. Angelini， N. Shukla，“提供h2s的西地那非（ACS6）对动脉内皮细胞超氧化物形成和gp91phox表达的抑制作用：蛋白激酶A和G的作用”，英国药理学杂志，第155期。7 (2008): 984-994, https://doi.org/10.1038/bjp.2008.326.This关注的表达是对上述文章的关注，该文章于2009年1月29日在线发表在Wiley在线图书馆（wileyonlinelibrary.com）上，并已由该杂志总编辑psamter Ferdinandy；英国药理学会；约翰·威利&；在发表了关于图8中一个斑点与其他地方发表的斑点的相似性以及它所代表的基础数据的担忧之后，该杂志进行了调查，同意了关注表达。由于时间已过，发件人无法提供令人满意的解释，也无法提供原始数据。然而，由于对数据和结果的完整性的担忧无法得到解决，该杂志发表了这份关注表达。作者g.d.a.同意本关注表达。
EXPRESSION OF CONCERN: H2S-Donating Sildenafil (ACS6) Inhibits Superoxide Formation and gp91phox Expression in Arterial Endothelial Cells: Role of Protein Kinases A and G
EXPRESSION OF CONCERN: S. Muzaffar, J. Y. Jeremy, A. Sparatore, P. Del Soldato, G. D. Angelini, and N. Shukla, “H2S-Donating Sildenafil (ACS6) Inhibits Superoxide Formation and gp91phox Expression in Arterial Endothelial Cells: Role of Protein Kinases A and G,” British Journal of Pharmacology 155, no. 7 (2008): 984–994, https://doi.org/10.1038/bjp.2008.326.
This Expression of Concern is for the above article, published online on 29 January 2009 in Wiley Online Library (wileyonlinelibrary.com), and has been issued by the journal Editor-in-Chief, Péter Ferdinandy; the British Pharmacological Society; and John Wiley & Sons Ltd.
The Expression of Concern has been agreed following an investigation by the journal after publication of concerns regarding the similarity of a blot in Figure 8 with one published elsewhere, and regarding the underlying data that it represents. The authors were unable to provide a satisfactory explanation and could not provide the original data given the time that had elapsed. However, the journal is issuing this Expression of Concern because the concerns regarding the integrity of the data and the results presented cannot be resolved.
Author G. D. A. agreed to this Expression of Concern.
期刊介绍：
The British Journal of Pharmacology (BJP) is a biomedical science journal offering comprehensive international coverage of experimental and translational pharmacology. It publishes original research, authoritative reviews, mini reviews, systematic reviews, meta-analyses, databases, letters to the Editor, and commentaries.
Review articles, databases, systematic reviews, and meta-analyses are typically commissioned, but unsolicited contributions are also considered, either as standalone papers or part of themed issues.
In addition to basic science research, BJP features translational pharmacology research, including proof-of-concept and early mechanistic studies in humans. While it generally does not publish first-in-man phase I studies or phase IIb, III, or IV studies, exceptions may be made under certain circumstances, particularly if results are combined with preclinical studies.
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