可见光诱导的1,5-氢原子转移（1,5- hat）自由基级联环化2-异氰基

Organic chemistry frontiers : an international journal of organic chemistry Pub Date : 2025-03-28 DOI:10.1039/d5qo00031a

Yafei Zhu , Penghua Zhang , Xingqin Tian , Xueqin Wang , Mi Wang , Cuimei Zhang , Jian Chen , Jing Zhang , Guanghui Lv , Yong Wu

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引用次数: 0

摘要

在此，我们报道了第一个可见光诱导的2-异氰酸双芳基级联环化通过1,5-氢原子转移合成菲菲啶的有吸引力的例子。该反应绕过了对碱、金属和高温的需要，使得制备的菲菲啉具有广泛的底物范围和优异的官能团相容性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Visible-light-induced radical cascade cyclization of 2-isocyanobiaryls via 1,5-hydrogen atom transfer (1,5-HAT)†

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Visible-light-induced radical cascade cyclization of 2-isocyanobiaryls via 1,5-hydrogen atom transfer (1,5-HAT)†

Herein, we reported the first attractive example of visible-light-induced radical cascade cyclization of 2-isocyanobiaryls for the synthesis of phenanthridines via 1,5-hydrogen atom transfer. The reaction circumvents the need for a base, metals, and high temperature, enabling the preparation of phenanthridines with a broad substrate scope and excellent functional group compatibility.

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来源期刊

Organic chemistry frontiers : an international journal of organic chemistry

CiteScore

7.80

自引率

0.00%

发文量