Mikolaj Przydacz, Giorgio I Russo, Brian J Linder, Howard B Goldman
{"title":"男性压力性尿失禁的膨胀剂。","authors":"Mikolaj Przydacz, Giorgio I Russo, Brian J Linder, Howard B Goldman","doi":"10.1016/j.euf.2025.03.010","DOIUrl":null,"url":null,"abstract":"<p><p>Bulking agents have attracted interest as a minimally invasive treatment for postprostatectomy stress urinary incontinence (PPSUI). The efficacy of bulking agents is modest and success rates vary widely, with short-term improvements reported for some patients but with a decline in durability over time. In comparison to artificial urinary sphincters and male slings, bulking agents are associated with lower continence rates and higher risk of failure. Complication rates depend on the agent used, but most adverse effects are mild. Patient selection is critical, with better outcomes observed for mild to moderate incontinence. Although newer agents show promise, standardized protocols and long-term studies are needed to clarify the efficacy of new bulking agents in PPSUI management. PATIENT SUMMARY: Bulking agents can help temporarily with urine leakage after prostate surgery, but they are less effective than other treatments. Their benefits often fade over time, and more research is needed to assess their long-term usefulness.</p>","PeriodicalId":12160,"journal":{"name":"European urology focus","volume":" ","pages":""},"PeriodicalIF":4.8000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bulking Agents in Male Stress Incontinence.\",\"authors\":\"Mikolaj Przydacz, Giorgio I Russo, Brian J Linder, Howard B Goldman\",\"doi\":\"10.1016/j.euf.2025.03.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Bulking agents have attracted interest as a minimally invasive treatment for postprostatectomy stress urinary incontinence (PPSUI). The efficacy of bulking agents is modest and success rates vary widely, with short-term improvements reported for some patients but with a decline in durability over time. In comparison to artificial urinary sphincters and male slings, bulking agents are associated with lower continence rates and higher risk of failure. Complication rates depend on the agent used, but most adverse effects are mild. Patient selection is critical, with better outcomes observed for mild to moderate incontinence. Although newer agents show promise, standardized protocols and long-term studies are needed to clarify the efficacy of new bulking agents in PPSUI management. PATIENT SUMMARY: Bulking agents can help temporarily with urine leakage after prostate surgery, but they are less effective than other treatments. Their benefits often fade over time, and more research is needed to assess their long-term usefulness.</p>\",\"PeriodicalId\":12160,\"journal\":{\"name\":\"European urology focus\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2025-03-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European urology focus\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.euf.2025.03.010\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European urology focus","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.euf.2025.03.010","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Bulking agents have attracted interest as a minimally invasive treatment for postprostatectomy stress urinary incontinence (PPSUI). The efficacy of bulking agents is modest and success rates vary widely, with short-term improvements reported for some patients but with a decline in durability over time. In comparison to artificial urinary sphincters and male slings, bulking agents are associated with lower continence rates and higher risk of failure. Complication rates depend on the agent used, but most adverse effects are mild. Patient selection is critical, with better outcomes observed for mild to moderate incontinence. Although newer agents show promise, standardized protocols and long-term studies are needed to clarify the efficacy of new bulking agents in PPSUI management. PATIENT SUMMARY: Bulking agents can help temporarily with urine leakage after prostate surgery, but they are less effective than other treatments. Their benefits often fade over time, and more research is needed to assess their long-term usefulness.
期刊介绍:
European Urology Focus is a new sister journal to European Urology and an official publication of the European Association of Urology (EAU).
EU Focus will publish original articles, opinion piece editorials and topical reviews on a wide range of urological issues such as oncology, functional urology, reconstructive urology, laparoscopy, robotic surgery, endourology, female urology, andrology, paediatric urology and sexual medicine. The editorial team welcome basic and translational research articles in the field of urological diseases. Authors may be solicited by the Editor directly. All submitted manuscripts will be peer-reviewed by a panel of experts before being considered for publication.