{"title":"利用造影剂和凝固剂的弛豫性开发磁共振成像模型的 T1 和 T2 值估算方法。","authors":"Hiroki Okada, Norikazu Koori, Hatsune Shimizu, Shohei Yamamoto, Tetsuya Komatsuzaki, Hiraku Fuse, Kota Sasaki, Shin Miyakawa, Kenji Yasue, Masato Takahashi","doi":"10.1007/s12194-025-00900-7","DOIUrl":null,"url":null,"abstract":"<p><p>The T<sub>1</sub> and T<sub>2</sub> values of magnetic resonance imaging phantoms used by researchers should be equivalent to those of the target tissue. However, this is difficult to achieve because of variations in the phantoms depending on the type and concentration of contrast agents and coagulants. The aim of this study was to elucidate the utility of a determination equation derived using the relaxivity of the contrast agent and coagulant. We prepared phantoms using 0.05-10 mmol L<sup>-1</sup> contrast agent (Gadovist<sup>®</sup>; Bayer Yakuhin, Ltd., Osaka, Japan) and 0.1-5.0 wt% agar (agar, powder [010-15815]; Fujifilm Wako Pure Chemical Corporation, Osaka, Japan) and measured their T<sub>1</sub> and T<sub>2</sub> values. Determination equations for T<sub>1</sub> and T<sub>2</sub> values were derived using the relaxivity calculated from the T<sub>1</sub> and T<sub>2</sub> values of the contrast agent and coagulant. Subsequently, the determined values were compared with the measured values. The error rate of the determined T<sub>1</sub> and T<sub>2</sub> values were 7.66 ± 6.60% and 5.66 ± 4.05%, respectively, with correlation coefficients of 0.996 and 0.999. These results indicate that this method enables easy and highly accurate estimation of T<sub>1</sub> and T<sub>2</sub> values in MRI phantoms.</p>","PeriodicalId":46252,"journal":{"name":"Radiological Physics and Technology","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development of estimation method for T<sub>1</sub> and T<sub>2</sub> values using the relaxivity of contrast agent and coagulant for a magnetic resonance imaging phantom.\",\"authors\":\"Hiroki Okada, Norikazu Koori, Hatsune Shimizu, Shohei Yamamoto, Tetsuya Komatsuzaki, Hiraku Fuse, Kota Sasaki, Shin Miyakawa, Kenji Yasue, Masato Takahashi\",\"doi\":\"10.1007/s12194-025-00900-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The T<sub>1</sub> and T<sub>2</sub> values of magnetic resonance imaging phantoms used by researchers should be equivalent to those of the target tissue. However, this is difficult to achieve because of variations in the phantoms depending on the type and concentration of contrast agents and coagulants. The aim of this study was to elucidate the utility of a determination equation derived using the relaxivity of the contrast agent and coagulant. We prepared phantoms using 0.05-10 mmol L<sup>-1</sup> contrast agent (Gadovist<sup>®</sup>; Bayer Yakuhin, Ltd., Osaka, Japan) and 0.1-5.0 wt% agar (agar, powder [010-15815]; Fujifilm Wako Pure Chemical Corporation, Osaka, Japan) and measured their T<sub>1</sub> and T<sub>2</sub> values. Determination equations for T<sub>1</sub> and T<sub>2</sub> values were derived using the relaxivity calculated from the T<sub>1</sub> and T<sub>2</sub> values of the contrast agent and coagulant. Subsequently, the determined values were compared with the measured values. The error rate of the determined T<sub>1</sub> and T<sub>2</sub> values were 7.66 ± 6.60% and 5.66 ± 4.05%, respectively, with correlation coefficients of 0.996 and 0.999. These results indicate that this method enables easy and highly accurate estimation of T<sub>1</sub> and T<sub>2</sub> values in MRI phantoms.</p>\",\"PeriodicalId\":46252,\"journal\":{\"name\":\"Radiological Physics and Technology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-03-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Radiological Physics and Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s12194-025-00900-7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiological Physics and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12194-025-00900-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Development of estimation method for T1 and T2 values using the relaxivity of contrast agent and coagulant for a magnetic resonance imaging phantom.
The T1 and T2 values of magnetic resonance imaging phantoms used by researchers should be equivalent to those of the target tissue. However, this is difficult to achieve because of variations in the phantoms depending on the type and concentration of contrast agents and coagulants. The aim of this study was to elucidate the utility of a determination equation derived using the relaxivity of the contrast agent and coagulant. We prepared phantoms using 0.05-10 mmol L-1 contrast agent (Gadovist®; Bayer Yakuhin, Ltd., Osaka, Japan) and 0.1-5.0 wt% agar (agar, powder [010-15815]; Fujifilm Wako Pure Chemical Corporation, Osaka, Japan) and measured their T1 and T2 values. Determination equations for T1 and T2 values were derived using the relaxivity calculated from the T1 and T2 values of the contrast agent and coagulant. Subsequently, the determined values were compared with the measured values. The error rate of the determined T1 and T2 values were 7.66 ± 6.60% and 5.66 ± 4.05%, respectively, with correlation coefficients of 0.996 and 0.999. These results indicate that this method enables easy and highly accurate estimation of T1 and T2 values in MRI phantoms.
期刊介绍:
The purpose of the journal Radiological Physics and Technology is to provide a forum for sharing new knowledge related to research and development in radiological science and technology, including medical physics and radiological technology in diagnostic radiology, nuclear medicine, and radiation therapy among many other radiological disciplines, as well as to contribute to progress and improvement in medical practice and patient health care.